University of Vermont and State Agricultural College

Cornelis Van't Veer

Kenneth G Mann

Michael Kalafatis

Persons having the Factor V,mutation and a lower than average plasma level of TFPI have been found to be at elevated risk of thrombosis. Prophylactic methods for reducing the risk of thrombosis employ the administration of TFPI to achieve higher levels in the plasma.

Thrombosis prophylaxis for factor Vleiden carriers

Persons having the Factor V.sup.LEIDEN mutation and a lower than average plasma level of TFPI have been found to be at elevated risk of thrombosis. Prophylactic methods for reducing the risk of thrombosis employ the administration of TFPI to achieve higher levels in the plasma.

Growing community of inventors

Burlington, VT, United States of America

Cornelis Van't Veer