Arcus Biosciences, Inc.

Corinne Nicole Foley

Jay Patrick Powers

Manmohan Reddy Leleti

Jaroslaw Kalisiak

Joel Worley Beatty

Eric Newcomb

Anh Thu Tran

Tezcan Guney

Rebecca Louise Grange

Brandon Reid Rosen

Dillon Harding Miles

Debashis Mandal

Erick Allen Lindsey

Yongli Su

Balint Gal

Steven Donald Jacob

Srinivas Paladugu

Shiwei Qu

Manjunath Lamani

Eric Thomas Newcomb

Compounds that are inhibitors of at least one of ARG1 and ARG2, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by ARG1 and ARG2 are also described herein.

Inhibitors of ARG1 and/or ARG2

Compounds of Formula I that inhibit AXL, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer, that are mediated, at least in part, by AXL.

Compounds as inhibitors of AXL

Compounds that are inhibitors of at least one of the ARG1 and ARG2, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by ARG1 and ARG2 are also described herein.

Arginase inhibitors

Growing community of inventors

San Carlos, CA, United States of America

Corinne Nicole Foley