Biomerieux, Inc.

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Corine Fulchiron

Frédéric Pinston

Dominique Decaux

Guillaume Sutra

Laurent Drazek

Hervé Rostaing

Denis Desseree

Lorène Allano

Guillaume Perrin

Guillaume Boissier

Lorette Lapierre

Léontine Jacolin

Christophe Tachier

Philippine Barlas

Loréne Allano

Jean-Francois Gorse

Lorette Munoz

Delphine Archeny

Géraldine Durand

Jean-François Gorse

A method and a system for determining the presence of at least one determined microorganism in a Petri dish comprising one or more colonies of microorganisms and a culture medium, and a computer program product which, when executed, allows the method of the invention to be performed.

Method, system and computer program product for determining the presence of microorganisms and identifying said microorganisms

A locating method and system of determining a microorganism concentration of a fluid in a Petri dish is disclosed. The Petri dish includes a culture medium on which a seeding device is rotatable relative to the Petri dish. The seeding device distributes the fluid and includes at least one point of contact with the culture medium. The point of contact is associated with a contact zone.

Means, method and computer program product for determining the concentration level of microorganisms during a fluid analysis

An imaging system for generating images of biological samples having a surface, the system comprising: a sample support for supporting a biological sample in use; a plurality of illumination sources, the plurality of illumination sources being arranged around the sample support and each adapted to illuminate the biological sample, in use, from a different direction; an image capture device for capturing illumination which has impinged on the biological sample to thereby form an image of the sample; wherein at least one of the illumination sources direction is not perpendicular to the surface of the sample.

Imaging method and system for analyzing in-vitro biological samples

A method for defining an isolation area around an object of interest in a cell culture vessel, the method comprising the steps of: &#x2014;obtaining one or more images of the cell culture vessel using one or more of a plurality of illumination sources, each illumination source being capable of illuminating the vessel from a different direction; &#x2014;selecting an image or combination of images for further processing; &#x2014;applying a circular object detection transformation to identify one or more objects of interest being substantially circular objects in the cell culture vessel, which circular objects of interest are representative of isolated colonies in the cell culture vessel and determining the center of an object of interest; &#x2014;applying a binarizing step to obtain a binarized image of the object of interest and other objects, wherein the center of the binarized image corresponds to the center of the object of interest; &#x2014;iteratively forming concentric circles with increasing radius, wherein the concentric circles are centered on the center of the binarized image; &#x2014;identifying coronas, wherein a corona is delimited by two circles having successive radius values; &#x2014;for each corona: determining the presence and the location of any other object located in the corona to determine the presence and the location of other objects; &#x2014;determining a clearance angle defining an angular sector free of other objects around the object of interest to define the isolation area around the object of interest.

Bio-imaging method

A method for enhancing an image of a biological sample, which biological sample has been grown in a vessel on a culture medium.

Bio-imaging method and system

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Serrieres de Briord, France

Corine Fulchiron