Ohio State Innovation Foundation

Corey Nislow

Gireesh Rajashekara

James Fuchs

Sally Miller

Xiulan Xu

Janet Antwi

Anand Kumar

Melvin Pascall

Ulyana Munoz Acuna

Esperanza Carcache De Blanco

Zilu Wan

Compounds and compositions of matter are provided that are small molecule antimicrobials. The compounds are selected from JH-144, TH-04 or TH-08 or combinations thereof. Compositions of matter are provided which in an embodiment may comprise a carrier, and in further embodiments may comprise a pharmaceutically acceptable excipient, film, biofilm or edible film. Methods of use are provided in which the composition may be administered to a subject in need thereof, and in an embodiment where the subject has a bacterial infection. Other embodiments provide the composition may be contacted with surface to eliminate or reduce bacteria.

Small molecule antimicrobials

The subject matter disclosed herein generally relates to modulators ofsubsp., derivatives thereof, formulations thereof, coated seeds, and methods of using such compounds to treat diseases such as bacterial canker in plants.

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Growing community of inventors

Columbus, OH, United States of America

Corey Nislow