Recherche Et Industrie Therapeutiques (r.i.t.)

Recherche Et Industrie Therapeutiques

Constant Huygelen

Lucia Dobrescu

Nathan Zygraich

Frans Van Wijnendaele

Vaccines against oedema disease of piglets comprising an effective amount of E. coli neurotoxin isolated from a culture of an E. coli serotype which is capable of causing piglet oedema disease and adsorbed on an adjuvant. The vaccines are administered by intramuscular or subcutaneous route.

Vaccines against oedema disease of piglets

Piglet colibacillosis vaccine for intramuscular or subcutaneous administration to pregnant sows comprising cell-free heat labile (LT) E. coli enterotoxin with an adjuvant and the method for preventing piglet colibacillosis consisting in administering said vaccine to pregnant sows from 3 to 6 weeks before farrowing.

Pre-farrowing pregnant sow piglet colibacillosis vaccines and process

The invention relates to live virus vaccines containing temperature-sensitive mutant strains of bovine Adenovirus, the cut-off temperature of said mutant strain being comprised between 39.degree. and 40.degree. C. The invention also relates to the induction of said temperature-sensitive mutant strains and to a vaccination method by intranasal administration of the obtained vaccines.

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Huldenberg, Belgium

Constant Huygelen