Baxter International Inc.

Baxter Healthcare Sa

Baxalta Gmbh

Cong Jiang

Ton That Hai

Paul Jeffrey Sanders

Mark Nordhaus

Sujatha Karoor

Tuan Bui

Ozlem Yardimci

David R Lamb

Larry Richard Brown

Kent Lane Lurvey

Arounaguiry Ambroise

Guohan Yang

Cliff Holmes

Jie Li

Catherine Quinn

Leo Martis

Michael Dockal

Vadim V Krongauz

Bennett Melnick

Susanne Till

Sabine Knappe

Ben Melnick

Fritz Scheiflinger

A method for immobilizing dyes and antimicrobial agents on a polymeric cover or housing for a medical device is disclosed and described. The surface may be that of a catheter, a connector, a drug vial spike, a bag spike, a prosthetic device, an endoscope, a surface of an infusion pump, a key pad, a touch screen or a handle. The surfaces may also be one or more of those associated with a infusion of a medicament or dialysis treatment, such as peritoneal dialysis or hemodialysis, where it is important that the working surface for the dialysis fluid be sterile. These surfaces include connectors for peritoneal dialysis sets or for hemodialysis sets, bag spikes, dialysis catheters, and so forth. A method for determining whether a surface has been sterilized, and a dye useful in so indicating, is also disclosed.

Antimicrobial housing and cover for a medical device

Therapeutic compositions capable of removing excess nitric oxide are provided. The therapeutic compositions include nitronyl nitroxide monoradicals, B12 derivatives, flavonoid derivatives, the like and combinations thereof. The therapeutic compositions can be utilized in a number of suitable applications, such as to prevent or treat intradialytic hypotension during dialysis.

Nitric oxide scavengers

The present invention relates to polymeric derivatives, which can be conjugated to an amino-containing drug to improve its in vivo properties. The polymeric derivative can subsequently be released to yield the drug in its native form. Methods of preparing and using these polymeric derivatives and drug conjugates are described.

Polymeric benzyl carbonate-derivatives

Therapeutic compositions are provided. The compositions include a single molecule that can display both antioxidant and carbonyl trapping properties. This can effectively reduce inflammation, oxidative stress and carbonyl stress, such as to prevent and/or treat cardiovascular disease and inflammatory diseases in kidney disease patients.

Compositions capable of inhibiting reactive oxygen and carbonyl species

Methods of producing zirconium oxide compositions and using same are provided. The zirconium oxide compositions in crystalline form can be prepared by a synthetic process wherein the hydrolysis of zirconyl chloride and particle formation can be achieved simultaneously. Alternatively, the particle formation can occur first and then followed by hydrolysis with a base solution. The processes utilize a zirconyl salt solution that includes a zirconyl salt in isopropanol and water.

Method for processing a zirconium oxide composition in crystalline form

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Gurnee, IL, United States of America

Cong Jiang