J. Uriach & Cia, S.a.

Concepción Gonzalez

Carmen Almansa

Ma Carmen Torres

Compounds of formula I wherein: one of X or Y represents N and the other represents C; Rrepresents hydrogen, methyl, halogen, cyano, nitro, &#x2014;CHO, &#x2014;COCHor &#x2014;COOR; PRrepresents optionally-substituted aryl or heteroaryl; Rrepresents Calkyl, Chaloalkyl or &#x2014;NRR; Rrepresents hydrogen, Calkyl or arylCalkyl; Rrepresents hydrogen, Calkyl, arylCalkyl, &#x2014;CORor &#x2014;COOR; Rrepresents Calkyl or Chaloalkyl; aryl in the above definitions represents phenyl or naphthyl; and heteroaryl in the above definitions represents pyridine, pyrazine, pyrimidine or pyridazine, which can be optionally fused to a benzene ring. These compounds are useful as cyclooxygenase-2 inhibitors.

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Sant Boi de Llobregat, Spain

Concepción Gonzalez