Itf Research Pharma, S.l.u.

Concepción Nieto Magro

Jaime Moscoso Del Prado

Álvaro Acebrón Fernández

Dolores Blanco Lousame

Elena Pérez Hernando

Javier Suárez Almarza

ÁIvaro ACEBRÓN FERNÁNDEZ

The invention relates to intravaginal devices, in particular rings, comprising progesterone in a particular polymorphic purity, methods for making such devices and therapeutic uses of said devices. In particular, the intravaginal devices comprise a high amount of progesterone polymorph I and are useful in the treatment of infertility in a female subject.

Progesterone intravaginal devices

The present invention relates to the use of estriol in the preparation of a pharmaceutical formulation for vaginal administration with the capacity to self-limit the absorption of estriol, for the prevention and/or the treatment of urogenital atrophy in women, said women having a high probability of developing an estrogen-dependent tumor or suffering or having suffered from an estrogen-dependent tumor.

Treatment of vaginal atrophy in women with tumor pathology risk

The present invention relates to the use of estriol in the preparation of a pharmaceutical formulation for vaginal administration with the capacity to self-limit the absorption of estriol, for the prevention and/or the treatment of urogenital atrophy in women said women having a high probability of suffering from a cardiovascular pathology or suffering or having suffered from a cardiovascular pathology.

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Madrid, Spain

Concepción Nieto Magro