General Electric Company

Ge Healthcare Limited

Ge Healthcare UK Limited

Colin Steel

Victor Donald Samper

Marko Klaus Baller

Sajinder Kaur Luthra

Farah Shah

Robin Fortt

An HPLC module utilizes a combination of compound-dedicated hardware providing line clearance between differing radiosynthesis and includes multiple compound-dedicated HPLC inject valves, each inject valve directing a fluid to a serially-connected HPLC column and UV flowcell so as to prevent cross-contamination between differing radiopharmaceutical syntheses. The module provides a disposable fluid path from each UV flowcell allowing for radioactive detection, fraction collection, formulation and final product dispensing. In this manner, a level of GMP compliance is achieved that is suitable for meeting the requirements of an MHRA approved site-license.

Multi-stream high-pressure liquid chromatography module

A multi-stream optical interrogation flow cell () for a radiopharmaceutical includes a multiple flow cell body (-) defining a first elongate fluid flowpath (A-B-) therethrough for individually conducting a radiopharmaceutical therethrough in fluid isolation from other of the flow cell bodies. Each flow cell body further defines a first and second aligned UV transparent optical guides () and a first interrogation passageway (-) extending between the first and second optical guides such that a portion of the elongate first fluid flowpath intersects the interrogation passageway such that the radiopharmaceutical flows in between the first and second optical guides. The first and second interrogation passageways of all of the flow cell bodies are optically aligned so that a single interrogation beam is able to extend through each of the interrogation passageways.

Multi-stream spectrophotometer module

Growing community of inventors

London, United Kingdom

Colin Steel