Danisco US Inc.

Genencor International, Inc.

Other

Danisco US Inc., Genencor Division

Danisco A/s, Genencor Division

E.i. Dupont De Nemours and Company

Genecor International, Inc.

Colin Mitchinson

Peter Gualfetti

Frits Goedegebuur

Edmund A Larenas

Paulien Neefe

Anthony G Day

Andrew Shaw

Leif P Solheim

Mats Sandgren

Carol A Requadt

Jerry Stahlberg

William Dean Hitz

Timothy Fowler

Traci H Ropp

Scott Douglas Power

Robert Mark Caldwell

Bradley R Kelemen

Christopher Charles Barnett

Jay Ian Phillips

Aaron Kelley

Benjamin S Bower

Suzanne E Lantz

Wolfgang Aehle

Tom Tao Huang

George R England

Keith Dumont Wing

Lydia Dankmeyer

Pauline Teunissen

Richard Ray Bott

Richard L Antrim

Paul Joseph Fagan

Bruce Aaron Diner

Thomas P Graycar

Thijs Kaper

Dan J Wendt

Paulien Neefe-Kruithof

Mark Emptage

Brian G Lefebvre

J Bryan Jones

Steven Sungin Kim

Mian Li

Brad Kelemen

Christina Gutierrez

Christopher Ringer

Megan Yee Hsi

Amanda Kathleen Iverson

Chuanbin Liu

Bradley Kelemen

Landon Steele

George England

The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.

Glycosyl hydrolase enzymes and uses thereof

The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity, methods for hydrolyzing biomass material, and methods for reducing viscosity of biomass mixture using a composition comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity.

Method for reducing viscosity in saccharification process

The present disclosure is directed, in a first aspect, to the use of inverting beta-xylosidase enzymes to reduce byproduct formation and increase the yield of fermentation products, as well as, in a second aspect, to the use of retaining beta-xylosidase enzymes to improve production of alkyl-beta-xylopyranoside compounds, in a simultaneous saccharification and fermentation reactions.

Methods for improving the efficiency of simultaneous saccharification and fermentation reactions

Described herein are variants ofCBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.

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Disclosed are variants ofCeI7A (CBH1.1),CBH1 variant orCBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

Described herein is a composition useful for inducing expression of genes whose expression is under control of an inducible promoter sequence and methods for the compositions preparation and use.

Induction of gene expression using a high concentration sugar mixture

Disclosed are variants ofCel7A (CBH1.1),CBH1 variant orCBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

Variant humicola grisea CBH1.1

Disclosed are a number of homologs and variants ofCel7A (formerlycellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

CBH1 homologs and varian CBH1 cellulase

Described herein are variants ofCBH2, a Cel6A enzyme. The present invention provides novel cellobiohydrolases that have altered thermostability.

Methods are disclosed for the production of high concentrations of ethanol from biomass usingas the ethanologen.is grown under conditions of low impeller agitation with high concentration of insoluble solids in a saccharification-fermentation mixture during a simultaneous saccharification and fermentation reaction for the production of high concentrations of ethanol.

Process for simultaneous saccharification and fermentation for production of ethanol

This present disclosure relates to methods for improved production of proteins from a cell culture, particularly to culture components and conditions that can preferentially increase the expression of proteins produced from genes under the control of xylanase gene promoter sequences. The improved methods can be used for the production of enzyme compositions with enhanced xylanase and hemicellulolytic activity.

Altering enzyme balance through fermentation conditions

Growing community of inventors

Half Moon Bay, CA, United States of America

Colin Mitchinson