Perkinelmer Singapore Pte Limited

Colin Blackmore

Patrick Courtney

Alistair Fitch

Shab Ladha

Robert Alan Hoult

Steve Morris Bush

Steve Bush

A method for performing photo-modification of a biological sample, the method comprising: (a) irradiating the sample; (b) detecting one or more signals based on the irradiated sample; (c) using one or more processor means to analyze the detected signals and determine one or more irradiation parameters, and, (d) returning to (a) conditioned on the irradiation parameters. Thus modifications may be determined and executed interactively as an experiment progresses, and therefore directed towards specific structures and/or events identified as of particular interest in the course of the experiment.

Method of analysing a sample and apparatus therefor

A method of analysing a sample of biological material including components (to) tagged with respective fluorescent labels (to), comprises the steps of identifying a specific labeled component () to be monitored, and irradiating with an energy beam at least one region () of the sample which substantially surrounds said specific component. The energy beam modifies the optical properties of labels in the region () such that they are distinguishable from the label () associated with said specific component (). This assists the tracking of a specific component of interest as it moves through a sample. Apparatus for carrying out the method is also described.

Method and apparatus for analyzing a dynamic sample

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Welwyn Garden, United Kingdom

Colin Blackmore