Delalande S.a.

Colette A Douzon

Guy R Bourgery

Philippe L Dostert

Michel Langlois

Alain P Lacour

Patrick G Guerret

Jean-Francois R Ancher

Gisele C Mocquet

Phillippe L Dostert

Claude G Gouret

Jean A Coston

Claude J Gouret

Margherita Strolin-Benedetti

Jean-Alain Coston

N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.

N-Substituted phenyl-5-aminomethyl oxazolidinones and their method of use

A compound of the formula ##STR1## where R is selected from the group consisting of CH.sub.3 --CO--(CH.sub.2).sub.2 --O--, ##STR2## The compounds are useful in treating depression.

-N-substituted phenyl-5-methoxymethyl-2-oxazolidinones and

Method of treating the central nervous system troubles such as the Parkinson's disease and the senescence troubles, generally treated by the B type monoamine oxidase inhibitors, which comprises administering internally to a human being requiring such treatment a therapeutically effective amount of N-aryl 5-aminomethyl oxazolidine-2-one derivatives.

Therapeutical use of known 5-aminomethyl oxazolidine-2-one derivatives

N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines

There are disclosed 3-substituted phenyl-5-hydroxymethyl oxazolidinones which possess anti-depressant properties. The compounds are prepared by cyclizing, with ethyl carbonate, 1-substituted phenylamino-2,3-propanediol compounds.

5-Hydroxymethyl oxazolidinones

3-Parahydroxyphenyl-5-methylether-2-oxazolidinone compounds

Novel 5-hydroxymethyl oxazolidinones, the method of preparing them and

Compounds having the formula ##STR1## wherein R.sub.1 is hydrogen or CONHR.sub.7 and R.sub.7 is methyl or isopropyl, And wherein

3-Aryl 2-oxazolidinones, their process of preparation and their

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Paris, France

Colette A Douzon