Pennwalt Corporation

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Pennwalt Corportion

Clyde R Kinsolving

Vassil S Georgiev

Ronald C Griffith

Robert A Mack

As an anti-allergic treatment for warm-blooded animals, therapeutic amounts of a compound having the formula I (including acid salts thereof) or II are administered: ##STR1## where; R is OR.sup.4 or NHR.sup.5 in which R.sup.4 is hydrogen or lower alkyl, R.sup.5 is selected from phenyl and phenyl monosubstituted with halogen, lower alkyl, lower alkoxy, R.sup.1 and R.sup.2 are independently hydrogen or lower alkyl, and

Anti-allergy treatment using 2-(substituted

Alkali metal 2,5-dihydro-3-ethoxycarbonyl-2-[(substituted phenyl)amino]-4-furanyloxides are useful as anti-allergy agents.

Alkali metal 2,5-dihydro-3-ethoxycarbonyl-2-[(substituted

4,5-dihydro-4-oxo-2-[(2-trans-phenylcyclopropyl)amino]-3-furancarboxylic acids and derivatives are described.

4,5-dihydro-4-oxo-2-[(2-trans-phenylcyclopropyl)amino]-3-furancarboxylic

Substituted spiro[oxazolidine-5,2'-adamantane] compounds are described.

Substituted spiro[oxazolidine-5,2'-adamantane] compounds

5-Substituted and/or N-Substituted 4-azatricyclo [4.3.1.1.sup.3,8 ]undecane and 4-azatricyclo[4.3.1.1.sup.3,8 ]undecan-5-one compounds are prepared.

Substituted 4-azatricyclo[4.3.1.1.sup.3,8 ]undecane compounds

Treatment of warm-blooded animals infected with the herpes II virus by concurrently orally administering an antiviral agent effective against said virus and suitable for oral administration while topically applying the same or a different such agent to lesions caused by the infection. Effective antivirals include .alpha.,.alpha.-dimethyl-beta-adamantylethylamine and N,N-dialkyl,.alpha.,.alpha.-dimethyl-beta-adamantylethylamine.

Herpes II treatment

Warm-blooded animals are treated by administering to the animal a dosage, effective to alleviate the symptoms of measles, of a compound of the formula I or its acid salt: ##STR1## wherein R.sub.1 and R.sub.2 are selected from the class consisting of hydrogen and --CH.sub.3 and at least on pharmaceutically acceptable carrier, wherein the compound is 0.01 to 95% by weight of the composition.

Use of alpha, alpha-dialkyl adamantylethylamines to treat measles

Warm-blooded animals are treated by administering to the animal a dosage, effective to prevent or to alleviate the symptoms of herpes virus, type II, of a compound of the formula I or its acid salt: ##STR1## wherein R.sub.1 and R.sub.2 are selected from the class consisting of H and --CH.sub.3 ; and at least one pharmaceutically acceptable carrier, wherein the compound is 0.01 to 95% by weight of the composition.

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Fairport, NY, United States of America

Clyde R Kinsolving