E. R. Squibb Sons, Inc.

Other

Clyde L Sharik

Frank M Freeman

Anthony J Berejka

Michael J Amery

In accordance with the present invention an instantaneous delivery film useful in the delivery of a therapeutic agent to a wound site is provided. The present delivery film comprises a therapeutic agent, e.g. an enzyme or medicament, incorporated into a delivery material which forms the film. The delivery material is capable of rapidly dissolving in aqueous and saline solutions and comprises a water soluble and nonaqueous-solvent soluble film-forming polymer in an amount of from about 20 to about 100 percent by weight of the delivery material, and a plasticizer in an amount of from about 0 and 80 percent by weight of the delivery material. The present system is useful, for example, as a dry enzymatic debridement film suitable for the treatment of mammalian burns and ulcers.

Instantaneous delivery film

Electrically conductive adhesive material possessing good adhesive, cohesive, elastomeric and conductive properties is disclosed. The present adhesive material also has improved electrical stability since it is less susceptible to drying out in most ambients. The material comprises a plasticizer, a high molecular weight water-soluble polymer, uncrosslinked polyvinylpyrrolidone as the tackifier, and an electrolyte dopant.

Electrically conductive adhesive materials

In accordance with the present invention an improved adhesive structure for adhesion of an article to a fluid-emitting wound and the surrounding normal skin is disclosed. The adhesive structure comprises a first contact region comprised of a fluid-interactive adhesive material which provides adhesion to the wound and surrounding normal skin; a second contact region comprised of the same or a different adhesive material, which provides adhesion betweeen the first region, or another region integral with the first region, and the article; and, an absorbent region comprised of an absorbent fibrous, fabric or foam material intermediate the first and second regions whereby enhanced cohesion between the first and second regions and between the second region and the article, under conditions of heavy fluid emission, is provided.

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Trenton, NJ, United States of America

Clyde L Sharik