Other

University of Michigan

Clive Woffendin

Gary J Nabel

Zhi-yong Yang

Michael J Sheehy

Nin-Sun Yang

Jinsong Liu

Foreign genes may be stably introduced into T cells, monocytes, macrophages, dendrites, and hematopoietic stem cells by particle-mediated gene transfer. Introduction of an HIV protective gene into the cells of a patient infected with HIV by particle-mediated gene transfer is effective for the treatment of HIV infection.

Introduction of HIV-protective genes into cells by particle-mediated

This invention provides recombinant nucleic acid molecules for enhanced expression of genes that inhibit HIV gene expression. Cells transfected with these recombinant nucleic acids exhibit prolonged cell life. This invention also provides methods of treating individuals infected with HIV by introducing into them the transfected cells of this invention.

Recombinant nucleic acids for inhibiting HIV gene expression

Growing community of inventors

Ann Arbor, MI, United States of America

Clive Woffendin