University of California

Clinton Nishida

Bruce S Dunn

Jeffrey I Zink

Stacey A Yamanaka

Lisa M Ellerby

Joan S Valentine

Fumito Nishida

An active biological material encapsulated in a glass is formed using a sol-gel process. A metal alkoxide is mixed with water and exposed to ultrasonic energy at a pH.ltoreq.2 to form a single phase solution which is then buffered to a pH between about 5 and 7. The buffered solution is then mixed with the active biological material and the resultant gel is aged and dried. The dried product is a transparent porous glass with substantially all of the added active biological material encapsulated therein, the biological material retaining a high level of activity.

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Clinton Nishida