Basf Aktiengesellschaft

Novosis Pharma Ag

Novosis Ag

Clifton Zimmermann

Wilfried Fischer

Heribert Kuerten

Helmut Lewin

Ruediger Haas

Norbert Holl

Petra Huber

Hubert Kaffl

Juergen Wippel

Glen Mumford

A transdermal delivery system (TDS) having: a carrier layer (cover layer) impermeable to the substances/active ingredients to be delivered, a membrane permeable to the substances/active ingredients to be delivered, a reservoir containing substances/active ingredients to be delivered, the reservoir being provided between the carrier layer and the membrane; and a removable film, wherein the carrier layer and the membrane comprise electrodes such that the electrode(s) of the membrane serve(s) as counterelectrode(s) to the electrode (the electrodes) of the carrier layer, is disclosed.

Transdermal delivery system (TDS) with electrode network

The present invention refers to a flat self-adhering plaster having a multi-layer construction and reduced cold flow, characterized in that the layer of adhesive possesses a core of adhesive being a flowable adhesive and a ring of adhesive being an adhesive having reduced flowability which surrounds the core.

Patch with reduced cold flow

A transdermal delivery system (TDS) having: a carrier layer (cover layer) impermeable to the substances/active ingredients to be delivered; a membrane permeable to the substances/active ingredients to be delivered; a reservoir containing substances/active ingredients to be delivered, the reservoir being provided between the carrier layer and the membrane; and a removable film, wherein each of the carrier layer and the membrane comprise one or more electrodes such that the electrode(s) of the membrane serve(s) as counter electrode(s) to die electrode (the electrodes) of the carrier layer, is disclosed.

A moving web (1) is severed, after the intended length has been wound up, by fracture mechanical crack propagation starting from perforation cuts introduced by means of a laser system (9-11) into a web material embrittled by cooling (8) at the severance location.

Severing a web

A measuring element which senses the running of the solid of rotation is connected to the actual value input of a controller whose output signal is connected to a control element which acts upon a bearing which is adjustable perpendicularly to the axis.

Arrangement for the dynamic compensation of eccentricities of solids of

In order to generate precisely square-wave laser light pulses, a laser diode is fed by a current pulse generator which comprises a timing pulse generator and a power stage, which is driven by the latter and which is followed by a single-pole driver stage of high current having a rise time of a few nanoseconds for the laser diode which is connected in the circuit of a battery of capacitors.

Pulsed laser

A control loop comprising a control section, a set value/actual value comparator and a controller is expanded for ultraprecision measurements in such a way that, to detect measurement signals, the control variable connection between the controller output and the control section input is guided via a measured value transducer and, to evaluate and display the measured value, the correcting variable output of the controller is additionally connected to an evaluating circuit.

Growing community of inventors

Karlsruhe, Germany

Clifton Zimmermann