Macfarlan Smith Limited

Other

Johnson Matthey Public Limited Company

Clifton R Hamilton

The present disclosure relates to Form Z of acetic acid solvated hydrate of ponatinib hydrochloride. The present disclosure is also related to processes for the preparation of Form Z of acetic acid solvated hydrate of ponatinib hydrochloride. Further, the present disclosure also relates to pharmaceutical compositions comprising Form Z of acetic acid solvated hydrate of ponatinib hydrochloride and methods for treating disease using Form Z of acetic acid solvated hydrate of ponatinib hydrochloride.

Form of ponatinib

The invention relates to a crystalline methanol solvate or hydrate form of ABC, and an anhydrous form of ABC, that reversibly forms a hydrate of ABC. The invention is also directed to the preparation of the aforesaid solvate, hydrate, and anhydrous solid-state forms of ABC. Furthermore, the invention relates to pharmaceutical compositions comprising at least one of the aforesaid crystalline forms of ABC according to the invention, and the pharmaceutical use of at least one of the aforesaid crystalline forms of ABC according to the invention for treatment of a patient in need thereof.

Solid-state forms of Abemaciclib, their use and preparation

The invention relates to a crystalline pyridine or N,N-dimethylacetamide solvated solid-state form of idelalisib (IDB). The invention is also directed to the preparation of the aforesaid solvated solid-state forms of IDB. Furthermore, the invention is directed to the use of the aforesaid solvated solid-state forms of IDB.

Pyridine or N,N-dimethyl acetamide solvated solid state forms of solvated idelalisib, their use and preparation

An adjustable overhead suspension apparatus for a TV and a VCR includes an overhead support assembly mountable to a support structure, such as a ceiling or wall, a platform adapted to support a TV thereon, a pair of main bracket clamps attached to opposite ends of the platform and being adjustable in height for extending along opposite sides and engaging opposite top edges of the TV, fasteners for adjustably tightening the overhead support assembly to one of the platform and main bracket clamps to hold the TV at a desired tilted position about a horizontal axis, and a pair of auxiliary bracket clamps attached to and suspended below the platform and being adapted to support a VCR below the TV.

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Devens, MA, United States of America

Clifton R Hamilton