Biomerieux, Inc.

Biomerieux Vitek, Inc.

Clifford W Karl

Ron Robinson

Mark Joseph Fanning

Craig Drager

William Ernest Seaton

David Porat

Donald L Meyer

Arthur Rousmaniere

Thomas Burchard

Paul Springer

David Paul Chastain

James Clement Bishop

Andrew K Moore

Gregory R Maes

Michael James Justin

David B Shine

Garry R Tegeler

Roger James Morris

Jean-Pierre Bernard Gayral

Andrew G Zeigler

Dennis M Connor

Stephen Guerrera

Brent D Freiner

Bernard Jean Limon

Raymond M Shelton

Kent Smith

Gregg Flender

Daniel Ray Williams

An incubation station has a carousel for receiving a plurality of test sample cards. An even temperature and air flow distribution inside the carousel and incubation of the cards over time at the proper temperature was found to be critically dependent upon air flow characteristics within the incubation station. To optimize air flow, the carousel was given an open rear side that is exposed to an air distribution table having a cover plate placed adjacent to the rear surface of the carousel. The cover plate has a plurality of elongate slots positioned in a symmetrical ring-shaped pattern in registry with the carousel. The elongate slots are positioned at an angle relative to the slots in the carousel such that each carousel slot receives air from more than one slot. An extra fan was also added to the system to increase the flow of air into the air table. Scallop features on the carousel walls also promote even distribution of air flow over the cards. The carousel may be divided into a plurality of carousel segments to increase ease of removal and insertion of the carousel into the incubation station and manufacturability of the carousel.

Incubation station for test sample cards

Carousel for incubation station

An automatic sample testing machine for testing samples stored in test cards. The machine has a test sample positioning system for moving a tray containing a plurality of test sample cards and fluid receptacles among various stations in the machine. The machine has a diluting station for adding a predetermined quantity of diluent to the receptacles as needed. A pipetting station transfers fluid from one receptacle to another. A vacuum station is provided having a vacuum chamber moveable relative to the tray between upper and lower positions. The chamber cooperates with the tray to make a sealing engagement with the top surface of the tray when it is lowered to the lower position. A vacuum generator supplies vacuum to the chamber. When the vacuum is released from the chamber, the fluid samples are loaded into the cards from the receptacles. The test sample positioning system moves the tray to a cutting and sealing station and then to an incubation station and loads the cards one at a time into a carousel within the incubation station. A test card transport station transports the test cards from the incubation station to an optical reading station, where optical measurements (e.g., transmittance and/or fluorescence optical testing) is conducted on the wells of the card. When the card has been read, it is either moved back to the incubation station for additional incubation and reading or transferred to a card disposal system when the reading is complete.

Vacuum loading of test sample cards in an analytical instrument

Cutting and sealing station for test sample cards in an automated

Automatic sample testing method

Automatic sample testing machine

A disposal system for stacking card-like objects neatly in a magazine. The cards enter the disposal system via a card entrance slot. A push plate located adjacent the slot pushes the cards past a pair of resilient snap elements in the sides of the magazine. A pressure plate is located behind the snap elements and biases the cards that have been pushed over the snap elements forward towards the rear of the snap elements. The cards are maintained in a stacked condition between the snap elements and the pressure plate. When a card is inserted into the card slot, the push plate is operated to an extended position, in which it pushes the card past the snap elements against the cards stacked between the snap elements and the pressure plate. The push plate then retracts, so as to enable another card to enter into the card slot. The user of the machine removes the magazine from the machine when the need arises or when the magazine is fully loaded with cards.

Stacking disposal system for test sample cards or other similarly shaped

Growing community of inventors

St. Louis, MO, United States of America

Clifford W Karl