Cordis Corporation

C. R. Bard, Inc.

Ethicon, Gmbh

Children's Medical Center Corporation

Mentor Worldwide LLC

Cardinal Health Switzerland 515 Gmbh

Donald Francis Depalma

Clifford J. Dwyer

Kirk L. Johnson

Alfredo Castaneda

Clifford Dwyer

Leo B Kriksunov

Timothy Robinson

Michael F Weiser

Duan Li Ou

Donald Francis DePalma

Lamar Kirchhevel

Mark L Mathis

Craig L Bonsignore

Luis A Davila

Robert P Letendre

Frederick Feller, Iii

David J Wilson

Michael V Williamson

Frederick Iii Feller

Robert J Tannhauser

Kirk L Johnson

Kenneth S Solovay

Krasimira Hristov

James A Fleming

James E Lock

Dennis Kujawski

William L Howat

Carol A Ryan

Tara Schaneville

James R Kershner

Juan Borges

Tara L Schaneville

Frederick Feller Iii

Provided are rapidly cross-linkable silicone compositions, systems, kits, and methods for filling implanted medical devices in situ, the implanted medical devices, including for example, body implants and tissue expanders, the compositions including a platinum divinyl disiloxane complex; a low viscosity vinyl terminated polydimethylsiloxane; a low viscosity hydride terminated polydimethylsiloxane; and a silicone cross-linker, where the rapidly cross-linkable silicone composition has a viscosity of &#x2264;150 cPs for &#x2265;1 min. post-preparation and &#x2264;300 cPs&#x2264;5 min. post-preparation, at ambient temperature.

Silicone compositions rapidly cross-linkable at ambient temperatures and methods of making and using same

An implant-delivery sleeve may comprise an enclosure having at least one opening and at least one vent conduit. The vent conduit may extend along a surface of the enclosure to assist in removing fluids (e.g., blood and air) from the tissue pocket to facilitate implantation of the implant.

Delivery sleeve

The present invention is directed to a prosthesis and method for treating, repairing, and/or replacing an abdominal aortic aneurysm. The prosthesis includes a coiled stent comprised of shape memory material having first and second anchoring zones and an intermediate zone. The prosthesis also includes graft material engaging at least a portion of the stent. During delivery of the prosthesis, the stent is in a substantially straight longitudinal configuration, and after delivery of the prosthesis the stent is returned to a coiled configuration. The diameter of the prosthesis may be adjusted by controlling the degree to which the stent is coiled.

Prosthesis comprising a coiled stent and method of use thereof

A stent-graft fabricated from a thin-walled, high strength material provides for a more durable and lower profile endoprosthesis. The stent-graft comprises one or more stent segments covered with a fabric formed by the weaving, knitting or braiding of a biocompatible, high tensile strength, abrasion resistant, highly durable yarn such as ultra high molecular weight polyethylene. The one or more stent segments may be balloon expandable or self-expanding. The fabric may be attached to the stent segments utilizing any number of known materials and techniques. The fabric may be attached to the stent segments utilizing an attachment device that secures the fabric to a strut of the stent segment by sandwiching the fabric between itself and the stent strut.

Graft material attachment device and method

An apparatus for delivering an implant within a lumen or passageway is provided. The apparatus comprises a flexible, hollow outer member having an elongated section that is inserted into and navigated through the lumen of passageway. The implant is mounted within the distal end of the elongated section. An elongated fluid chamber is defined within the outer member between two valves or seals. The valves or seals permit fluid flow in a pre-determined direction during loading of fluid into the chamber, but prevent fluid to exit the chamber during deployment of the implant. A shaft is in contact with the proximal end of the fluid column. During deployment, the shaft is held in a fixed position and the outer member actuated in a proximal direction. The implant exerts compressive forces on the outer member as it is actuated proximally. These forces are transmitted to the fluid column which resists buckling.

Implant delivery apparatus

A method for pre-loading an implant delivery apparatus and for delivering an implant is provided. An implant is mounted within the distal end of an elongated section of a delivery apparatus. After the implant is mounted within the elongated section, fluid is drawn into a chamber within the delivery apparatus that is proximal to the implant. This is accomplished by drawing fluid, such as a biocompatible liquid, into the chamber by applying pressure to a port. The fluid is trapped inside the chamber forming a liquid column. The elongated section is advanced through a lumen or passageway delivering the implant to a desired location. A shaft, which is in communication with the fluid column, is held stationary and the elongated section retracted deploying the implant. As the elongated section is retracted, the implant exerts forces upon the elongated section that are transmitted to the fluid column which resists buckling.

Method for preparing and employing an implant delivery apparatus

A system, apparatus, and method for treating, repairing, an aneurysm, preferably an aortic aneurysm, and most preferably, an abdominal aortic aneurysm as described herein. The systems, devices, and methods described herein include a first prosthesis or stent gasket, and at least one second prosthesis for bypassing the aneurysm. The first prosthesis is configured and adapted to accommodate a section of artery upstream of the aneurysm, wherein the section is unsuitable for anchoring a typical first prosthesis.

Supra-renal anchoring prosthesis

The invention is a system, apparatus, and method for treating or repairing, an aneurysm in a large vessel, such as a thoracic aneurysm. The systems, devices, and methods of the present invention include a first prosthesis for anchoring a proximal end of the system in the blood vessel, a second prosthesis for anchoring a distal end of the system, and at least one third second prosthesis for bypassing the aneurysm, the first prosthesis optionally further comprising a seat or the like adapted and configured to receive the third prosthesis.

Thoracic aneurysm repair prosthesis and system

A stent-graft fabricated from a thin-walled, high strength material provides for a more durable and lower profile endoprosthesis. The stent-graft comprises one or more stent segments covered with a fabric formed by the weaving, knitting or braiding of a biocompatible, high tensile strength, abrasion resistant, highly durable yarn such as ultra high molecular weight polyethylene. The one or more stent segments may be balloon expandable or self-expanding. The fabric may be attached to the stent segments utilizing any number of known materials and techniques.

Abrasion resistant vascular graft

A delivery apparatus for a self-expanding stent is disclosed. The apparatus has an outer sheath forming an elongated tubular member having distal and proximal ends and an inside and outside diameter. The apparatus also includes an inner shaft located coaxially within the outer sheath. The inner shaft has a distal end, a proximal end and longitudinal axis extending therebetween. At least a portion of the inner shaft is made from a flexible coiled member. The shaft preferably includes a stop attached thereto, the stop being proximal to the distal end of the sheath. Lastly, the apparatus includes a self-expanding stent located within the outer sheath, wherein the stent makes frictional contact with the outer sheath and the shaft is disposed coaxially within a lumen of the stent. During deployment of the stent, the stent makes contact with the stop.

Delivery apparatus for a self-expanding stent

A delivery apparatus for self-expanding stents may be utilized to safely deliver stents to a target site. The apparatus has an outer sheath forming an elongated tubular member having distal and proximal ends and an inside and outside diameter. The apparatus also includes an inner shaft located coaxially within the outer sheath. The inner shaft has a distal end, a proximal end and a longitudinal axis extending therebetween. At least a portion of the inner shaft is made from a flexible coiled member. The shaft preferably includes a stop attached thereto, the stop being proximal to the distal end of the sheath. Lastly, the apparatus includes a self-expanding stent located within the outer sheath, wherein the stent makes frictional contact with the outer sheath and the shaft is disposed coaxially within a lumen of the stent. During deployment of the stent, the stent makes contact with the stop.

A delivery device for intraluminally positioning and controllably releasing a vascular prosthesis includes an elongate delivery sheath and a control handle at the proximal end of the device. The handle has components movable and arranged to define at least three relative positions including (1) an implant capture position in which the sheath fully encloses and contains the implant, (2) an intermediate position in which the implant is partially deployed but in which the trailing end of the implant remains attached to the delivery device, and (3) a release position in which the implant has been freed from the delivery device and fully released within the blood vessel. The movable parts of the handle include a shifting mechanism that must be operated deliberately through a detent by the physician to enable the handle to be manipulated from one position to the other.

Endoprosthesis delivery catheter with sequential stage control

An endoprosthesis assembly adapted to be positioned within a body lumen includes a resilient, self-expanding anchor attached to a tubular graft. The endoprosthesis can be recaptured in a delivery device to enable repositioning or removal of the endoprosthesis at any time prior to complete deployment of the endoprosthesis in the patient. The delivery device includes an outer tubular member that carries the endoprosthesis in a radially contracted configuration and an elongate inner tubular member that extends through the prosthesis and beyond the distal end of the outer tubular member. A retainer is carried by the inner member that engages and retains the proximal end of the endoprosthesis relative to the inner member until the endoprosthesis is released. The inner member is formed from an alloy that has superelastic characteristics throughout the range of body temperatures to which it will be exposed to enhance the column strength and pushability of the device while providing a high level of longitudinal flexibility.

Growing community of inventors

Weston, FL, United States of America

Clifford Dwyer