Takeda San Diego, Inc.

Other

Clifford D Mol

Douglas R Dougan

Gyorgy Snell

Ellen Chien

Alexei Brooun

Ciaran N Cronin

Bi Ching Sang

Hua Zou

Michelle L Kraus

Hans E Krokan

Geir Slupphaug

Bodil Kavli

John A Tainer

Kheng Lim

Andrew John Jennings

Mark Knuth

Oleg Brodsky

Garret Textor

Ellen Y T Chien

Novel cytosine-, thymine- and uracil-DNA glycosylases, subcellular localization peptides, nucleic acid molecules containing the same, methods of identifying such enzymes and their use in various methods including mutagenesis, cell killing and DNA sequencing and modification, are desired.

DNA glycosylases and their use

Provided are crystals relating to human phosphodiesterase 4-D3 (PDE4-D3), methods for forming crystals comprising PDE4-D3 and crystals comprising PDE4-D3 co-crystallized with a ligand molecule, and methods of using crystals comprising PDE4-D3.

Crystallization of the catalytic domain of human phosphodiesterase 4-D3 (PDE4-D3)

Provided are crystals relating to the carboxyltransferase domain of human Acetyl-Coenzyme A Carboxylase 2 and its various uses.

Crystallization of carboxyltransferase domain of Acetyl-CoEnzyme A Carboxylase 2 with a ligand

Provided are crystals relating to human mitogen-activated protein kinase kinase2 (MAPKK2), also known as MAPK/ERK Kinase2 (MEK2) and its various uses.

Crystallization of MAPK/ERK Kinase 2

Provided are crystals relating to Protein kinase B&#x3b1;/AKT1 and its various uses.

Crystallization of protein kinase B&#x3b1;/AKT1

Provided are crystals relating to the autoinhibited structure of c-KIT tyrosine kinase (c-KIT) and its various uses.

Crystallization of c-KIT tyrosine kinase leading to autoinhibited crystal structure

Provided are crystals and structure coordinates relating to FMS-like tyrosine kinase 3 and its various uses.

Crystallization of FMS-like tyrosine kinase 3

Provided are crystals relating to human Glucocorticoid Receptor and its various uses.

Crystallization of Glucocorticoid Receptor

Novel cytosine-, thymine- and uracil-DNA glycosylases, subcellular localization peptides, nucleic acid molecules containing the same, methods of identifying such enzymes and their use in various methods including mutagenesis, cell killing and DNA sequencing and modification, are described.

Growing community of inventors

San Diego, CA, United States of America

Clifford D Mol