University of Saskatchewan

Clement R Rioux

Andrew A Potter

Anthony Bernard Schryvers

Richard J Harland

Michael Theisen

Cloning and expression of genes encodingtransferrin-binding proteins are described. The transferrin-binding proteins can be used in vaccine compositions for the prevention and treatment ofinfections, as well as in diagnostic methods for determining the presence ofinfections.

Cloning and expression of Haemophilus somnus transferrin-binding proteins

Cloning and expression of genes encoding transferrin-binding proteins are described. The transferrin-binding proteins can be used in vaccine compositions for the prevention and treatment of infections, as well as in diagnostic methods for determining the presence of infections.

Vaccine compositions comprising Haemophilus somnus transferrin-binding proteins and methods of use

Novel vaccines for use in the prevention and treatment of H. somnus infections are disclosed. The vaccines contain epitopes from LppA, LppB, LppC or combinations thereof. Also disclosed are the nucleotide sequences encoding these lipoproteins, vectors including these sequences, and host cells transformed with these vectors.

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Saskatoon, Canada

Clement R Rioux