Acell, Inc.

Cook Biotech, Inc.

Oregon Health & Science University

Cook Medical Technologies LLC

Cook Incorporated

Clay D Fette

Rodney W Bosley, Jr

F Joseph Obermiller

Matthew R Graham

Robert S Tullius

Abram D Janis

Benjamin T Kibalo

Michael C Hiles

Dusan Pavcnik

John A Kaufman

Brian L Bates

Umesh H Patel

Chad S McAlexander

Rodney W Bosley

Thomas A Osborne

Ram H Paul, Jr

Fred T Parker, Jr

Bhavin Shah

Joseph F Obermiller

Jason P Hodde

Fred T Parker

Jason A Mead

Paul D Amarant

Likang Chin

Chad S Mcalexander

Jr Rodney W Bosley

John Kaufman

Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.

Volumetric grafts for treatment of fistulae and related methods and systems

Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.

Particulate tissue graft with components of differing density and methods of making and using the same

Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.

Variable density tissue graft composition and methods of making and using the same

Described are stent graft devices and methods for their preparation and use. Expandable stent graft devices of the invention include inner and/or outer coverings uniquely applied and associated with surfaces of the stent. In certain described embodiments, bioremodelable materials such as ECM materials are vacuum pressed onto and/or around elements of a stent in the manufacture of a stent graft device.

Stent graft devices having collagen coating

Described are medical products, systems, and methods for treating fistulae having a primary opening, such as in the alimentary canal. Certain methods of the invention include providing an implantable material including a compliant sheet form biocompatible material, and forcing this sheet form biocompatible material into the primary opening so as to deform the sheet form biocompatible material to conform to and block the primary opening. The biocompatible material preferably comprises a remodelable material, for example, a remodelable extracellular matrix material such as submucosa.

Fistula graft with deformable sheet-form material

A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce homeostasis at an anatomical site.

Hemostatic device

A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.

Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures are used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the deployment of one or more vascular occlusion devices via a through-and-through percutaneous procedure that leaves the vascular occlusion device or devices in a through-and-through condition.

Vascular occlusion methods, systems and devices

Growing community of inventors

Palm Beach Gardens, FL, United States of America

Clay D Fette