Ecole Polytechnique Federale De Lausanne

Université De Lausanne

Claudio Pollo

Philippe Renaud

André Mercanzini

Andre Mercanzini

Jean-Philippe Thiran

Described herein are microelectrode array devices, and methods of fabrication, assembly and use of the same, to provide highly localized neural recording and/or neural stimulation to a neurological target. The device includes multiple microelectrode elements arranged protruding shafts. The protruding shafts are enclosed within an elongated probe shaft, and can be expanded from their enclosure. The microelectrode elements, and elongated probe shafts, are dimensioned in order to target small volumes of neurons located within the nervous system, such as in the deep brain region. Beneficially, the probe can be used to quickly identify the location of a neurological target, and remain implanted for long-term monitoring and/or stimulation.

Device for interacting with neurological tissue and methods of making and using the same

The system comprises at least three anchors (&#x2033;) intended to be attached to the patient and equipped with markers (&#x2033;), an insertion guide device () with an insertion guide () intended to be attached to said anchors (&#x2033;), an external calibration device () with at least three calibration markers (&#x2033;) corresponding to said markers (&#x2033;) and a planning and imaging software. The planning and imaging software is used to determine the position of a target point in the patient with respect to the markers (&#x2033;), the calibration device is used to calibrate and orient the insertion guide () of the insertion guide device () mounted on said calibration markers (&#x2033;) using the determination of the software before the insertion guide device is mounted on said markers (&#x2033;) attached to the patient.

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Lausanne, Switzerland

Claudio Pollo