Abiogen Pharma S.p.a.

Istituto Gentili S.p.a.

Claudio Menicagli

Giorgio Valentini

This invention relates to a method for the preparation and metering of substances, mixtures of substances and/or compounds in general, characterized by bacteriostatic and/or bactericidal activity, using a single pressurized container in which the substances, mixtures of substances and/or compounds in general are mixed with carbon dioxide in the form of vapor, liquid/vapor mixture or supercritical fluid for the purpose of mixing, dissolving, storing and dispensing at constant predetermined doses. The invention also relates to pressure containers suitable for dispensing the substances in accordance with the invention.

Method for preparation of biocides mixed with carbon dioxide in a pressurized container

A method is described for preparing mixtures of salts and/or other substances in general, including calcium and magnesium salts with carbon dioxide in pressurized containers, for the purpose of producing systems for the delivery of said mixtures in soluble form and at a predetermined and constant saline concentration, for a wide variety of applications. The mixtures containing the substances are prepared in a stirred reactor under a pressure of carbon dioxide, and from there are brought into use after they have been transferred into containers that are suitable for maintaining the internal pressure generated by the carbon dioxide in the form of vapor, in the form of a liquid/vapor mixture or under supercritical conditions.

Preparation and metering of components mixed with Co2

A process for the preparation of undenaturated triple helix collagen, starting form animal tendons or cutis, by extraction with diluted organic acids, precipitation with salts, optional gelation and/or lyophilization, tangential filtration. The obtained collagen shows favorable purity characteristics, is not allergenic and more effective in the healing processes than collagens obtained by known methods.

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Pisa, Italy

Claudio Menicagli