Survival Technology, Inc.

Meridian Medical Technologies, Inc.

Claudio Lopez

Stanley J Sarnoff

William R Tarello

N Lawrence Dalling

John Glyndwr Wilmot

William B Harvey

William R Pearson

George B Calkins

David Edward Spady

Linda A Gordon

Rudolph S Malooley

Thomas D Whalen

Daniel W Karcher

Hyung J Lee

Daniel M Karcher

An injection device includes a generally tubular outer body and a medicament cartridge assembly carried within the outer body. The cartridge assembly includes a glass container, a charge of medicament disposed within the glass container, iii) a plunger member rearwardly confining the medicament, and iv) a seal for sealing the forward portion of the glass container. A needle has a rearward end disposed proximate the seal, with the seal and needle being movable with respect to one another. A rigid needle cover member is normally maintained in an inoperative position and is movable relative to said body to a protective position wherein the needle cover member extends forwardly to cover the forward end of the needle. A releasable spring is releasable in response to a predetermined actuating procedure to drive a collet member forwardly within the outer body and thereby enable i) the cartridge assembly to move relative to the needle so that the rearward end of the needle pierces the seal to establish communication with the medicament, ii) the needle to move with respect to the body so that the needle projects outwardly from the forward end of the body, and iii) the needle cover to move relative to the body from the inoperative position to the protective position so that the needle cover member extends beyond the forward end of the needle.

Dental cartridge assembly auto-injector with protective needle cover

An autoinjector converted from an intramuscular to a subcutaneous mode of injection comprising a housing having a medicament cartridge assembly mounted within the housing means in a storage position for movement out of the storage position and a releasable stressed spring assembly for moving the medicament cartridge assembly means out of the storage position. The stressed spring assembly is operable in response to a manual actuating procedure which does not require compression of the subcutaneous tissue to effect an intramuscular mode of injection by moving the hypodermic needle of the cartridge assembly outwardly of the housing into the muscle tissue at the injection site of a user and a major portion of the liquid medicament of the cartridge assembly outwardly through the hypodermic needle into the muscle tissue of the user. An injection mode converting structure is secured in a subcutaneous mode position for converting the mode of injection effected by the stressed spring assembly from the intramuscular mode of injection to a subcutaneous mode of injection in which the needle cannot extend substantially beyond subcutaneous tissue at the injection site of the user and a major portion of the liquid medicament enters into the subcutaneous tissue.

Autoinjector converted from intramuscular to subcutaneous mode of

A stressed spring assembly for providing an operative stroke in cooperating relation with a medicament cartridge assembly of an auto-injector so as to inject a liquid medicament of the medicament cartridge assembly through a hypodermic needle of the medicament cartridge assembly into an injection site of the user. The stressed spring assembly includes a cap structure serving the plural purposes of (1) facilitating the securement of the cap structure and remainder of the auto-injection with the user's pocket, (2) alleviating the likelihood of an unwanted release of the releasable mechanism of the stressed spring assembly with a resultant unwanted movement of the hypodermic needle and an unwanted movement of the liquid medicament outwardly of the hypodermic needle by requiring two different manual movements for its removal, and (3) protecting against an unwanted contact with the hypodermic needle while in extended operative position after withdrawal from the injection site. The cap structure is formed of first and second members disposed in a fixed assembled position with respect to one another into which the first and second members are snap-fitted by a relative movement toward one another in an axial direction. Both members are of a configuration enabling them to be molded by corresponding die surfaces contained on two die members movable together and apart.

Conveniently carried frequent use auto-injector with improved cap

An autoinjector particularly suited to be carried on the person of a user comprising a housing defining an exterior configuration of a size and shape approximately the same as that of a conventional fountain pen including a housing body assembly of elongated generally cylindrical configuration and a separate housing cap structure of elongated generally cylindrical configuration having an elongated clip thereon. The housing cap structure is detachably secured to the housing body assembly in open ended telescopic relation with an opposite end portion thereof preferably by a childproof connection. A medicament cartridge assembly is mounted in a storage position within a forward end of an interior chamber within the housing body assembly and a releasable stressed spring assembly is carried by the housing body assembly adjacent the rearward end thereof. The housing cap structure serves the dual purposes of (1) facilitating the securement of the housing cap structure and body assembly with the user's pocket and (2) alleviating the likelihood of an unwanted release of the releasable stressed spring assembly with a resultant unwanted movement of the hypodermic needle of the cartridge assembly and an unwanted movement of the liquid medicament of the cartridge assembly outwardly of the needle.

Conveniently carried frequent use autoinjector

An automatic injector apparatus comprising an outer housing assembly, a hypodermic needle, first and second containers, a first liquid medicament ingredient in the first container and a second medicament ingredient in the second container, first and second pistons in the first and second containers respectively, a releasable stressed spring arrangement capable of being released twice, once for movement through a first piston moving stroke and second through a second piston moving stroke, a first releasing device operable in response to a first predetermined actuating procedure for accomplishing a first release of the spring arrangement so as to effect movement of the first piston through a liquid medicament ingredient moving stroke causing the liquid medicament ingredient to mix with the medicament ingredient in the second container to form liquid medicament and a second releasing device operable in response to a second actuating procedure for accomplishing a second release of the spring arrangement so as to effect movement of the second piston through an operative stroke causing the hypodermic needle to be moved into the muscle tissue of the patient and the liquid medicament to be moved through the needle into the muscle tissue of the patient.

Automatic medicament ingredient mixing and injecting apparatus

A disposable hypodermic syringe having a cylindrical barrel open at both its forward and rearward ends, with the forward tooled end having a necked down portion terminating in an annular flange having an outer diameter greater than that of the necked down portion and less than that of the cylindrical barrel, a stopper positioned in the necked down portion of the cylindrical barrel to seal off the tooled end of the barrel, a resilient plastic needle hub assembly fitted on the forward end of the cylindrical barrel. The hub assembly including a cylindrical body having both a forward and a rearward end, a nose portion extending forwardly from the forward end of the cylindrical body, a needle affixed to the nose portion away from the forward end of the cylindrical body, the cylindrical body being sized whereby it will resiliently fit over and engage the annular flange of the necked down portion of the cylindrical barrel to operatively retain the needle hub assembly on the cylindrical barrel with a sleeve of heat shrinkable plastic fitted over a portion of the hub assembly and contiguous cylindrical barrel whereby when heat is applied the sleeve will shrink to firmly engage the aforedescribed syringe portions and thereby provide an air tight seal between the hub body and the cylindrical barrel and in addition whereby the shrink tension will cause the hub body to more firmly engage the annular flange.

Disposable hypodermic syringe with plastic snap-on needle hub and heat

An automatic injecting device including an elongated housing assembly, a stressed spring assembly mounted within the housing assembly so as to be released in response to a predetermined manual acutation procedure, and a medicament cartridge assembly mounted within the housing assembly in cooperating relation with the stressed spring assembly comprising a hypodermic needle and a medicament container housing forward and rearward individual dosages of different relatively incompatible liquid medicaments mounted therein and separated by a deformable stopper. The medicament container is formed of glass and includes a cylindrical wall open at its rearward end and having an exteriorly flanged necked down forward end portion. A hub assembly connects the exteriorly flanged necked down forward end portion with the hypodermic needle. A separate fitment of molded plastic material is mounted within the interior of the cylindrical glass wall adjacent the necked down forward end portion thereof for radially inwardly deforming the stopper during operation and thereby providing an axial by-pass in the periphery thereof.

Plural dosage automatic injector with a by-pass fitment

A split hub assembly for use in conjunction with a cartridge assembly including a cylindrical cartridge tube having a necked down end terminating in an annular flange, the split hub assembly including a needle holder having a forward and a rearward end with a passage connecting the ends. A cylindrical body extends from the rearward end of the needle holder and surrounds a hollow spike extending from the rearward end of the needle holder in communication with the passage in the holder. A pluarlity of flexible segments extend rearwardly from the rearward end of the cylindrical body, each segment having a locking lip extending inwardly from the free end of the segment. The cylindrical body has a first locking portion adjacent the forward end portion of the body and a second locking portion adjacent the forward end portion of the body and a second locking portion adjacent the rearward end of the body. A locking portion comprising a cylindrical sleeve has an inturned locking member on its forward end which is sized to engage the first and then the second locking portion, whereby, with the locking member engaging the first locking portion on the cylindrical body and the flexible segments positioned over and around the annular flange on the necked end of the cartridge tube, rearward movement of the locking portion causes the cylindrical sleeve to engage the flexible segments and force them inwardly whereby the locking lips fit in against the rearward portion of the annular flange to secure the split hub assembly to the cartridge tube while the locking member engages the second locking portion to retain the locking means in position.

Split hub assembly for a necked down cartridge tube

A medicament discharging device and an expendable clip thereon containing a plurality of medicament cartridges. Each of the cartridges comprises a container, a dosage of medicament in the container, a hypodermic needle sealingly contained in a sterile condition in cooperating relation with the container and a movable wall means at one end of the container operable when moved through a discharging stroke to cause the sharpened end of the needle to move outwardly out of sealingly contained relation and into the muscle tissue of a patient and the medicament dosage to move outwardly of the container into the opposite end of the needle and out of the sharpened end thereof into the muscle tissue of the patient. The medicament discharging device comprises a portable manually engageable housing structure defining a medicament cartridge receiving station, a plunger mounted in the housing structure for movement through the medicament cartridge receiving station in repetitive operative cycles each of which includes a discharging stroke in one direction and a return stroke in the opposite direction, a manually actuatable mechanism for effecting movement of the plunger through an operative cycle, and a releasable connection between the housing structure and the clip for securing the same in operative relation so that successive cartridges in the clip will be presented in the medicament cartridge receiving station of the housing structure for injection in response to an operative cycle.

Multiple medicament cartridge clip and medicament discharging device

A dual mode automatic injector having a dual mode safety device for preventing the release of the stressed spring assembly except when it is desired to operate the medicament injecting assembly by the stressed spring assembly. The dual mode safety device comprises a first part including a pin portion disposed in a safety position extending through a central aperture in the rear wall of the housing assembly of the injector in release preventing relation with the stressed spring assembly for removal therefrom in response to a relative rearward movement with respect to the rear wall so as to permit an actuating movement to release the stressed spring assembly. The first part includes an automatic removal portion fixed to the rearward end of the pin portion. The automatic removal portion is of a size greater than the pin portion but less than the rear wall so as to present a forwardly facing surface spaced rearwardly from the rear wall operable to be engaged by a holding member while a moving member is moved forwardly into engagement with the rear wall to provide both a relative rearward removal movement for the pin portion and an actuating movement for the stressed spring assembly. The dual mode safety device also includes a separate second part and a connection between the first and second parts for (1) enabling the second part to be connected with the first part while the pin portion of the latter is in its safety position in a manual mode position wherein the first part is in rearward motion transmitting relation to the second part and (2) enabling the second part to be removed from the manual position while the pin portion of the first part is retained in its safety position. The second part includes a cap portion of a size and shape to be conveniently manually grasped by a user and moved rearwardly with respect to the housing assembly in order to effect the removal of the pin portion from its safety position when the second part is in its manual mode position.

Dual mode automatic injector

Apparatus for resuscitating a plurality of patients comprising four face mask assemblies each of which is operable to be operatively connected with a patient so as to permit fresh air to be supplied to the lungs of such patient and four bellows assemblies actuated by a cam track rotated either by a suitable clutched electric motor or by hand crank for delivering successive volumes of fresh air under pressure to each face mask assembly at a desired cyclical frequency wherein each cycle includes said fresh air delivery as a minor part thereof. Each face mask assembly has operatively associated therewith (1) a stale air exhaust valve assembly for permitting air expelled from the lungs of each patient during the remaining major part of each cycle associated therewith to be exhausted to atmosphere, (2) a medicament injector for selectively supplying a respiratory medicament dosage into the fresh air delivered to each face mask assembly, and (3) a pressure gauge for indicating the operative pressure adjacent the face mask assembly so as to enable the operator to readily determine a bronchoconstrictive condition of a patient operatively connected with the associated face mask assembly so that the associated selective medicament injector is selected to deliver medicament only during the minor cycle part when the fresh air is delivered.

Plural station resuscitator

A plural injection assembly comprising a plurality of separate injections capable of separate actuation and a holder for stably supporting the separate injectors together and for manually facilitating the sequential actuation thereof.

Growing community of inventors

Silver Spring, MD, United States of America

Claudio Lopez