Focus Surgery, Inc.

Eclipse Surgical Technologies, Inc.

Optical Coating Laboratory, Inc.

Labintelligence, Inc.

Onda Corporation

Claudio I. Zanelli, Intec Research Company

Claudio I Zanelli

Carl W Hennige

Narendra T Sanghvi

Francis J Fry

Michael J Rosinko

Steven A Daniel

Douglas R Murphy-Chutorian

Peter S Brown

Jeffrey J Giba

Robert L Cargill

Basil L Swaby

Stan DeMarta

Frank R Whitehead

Erich Gombocz

Gregg W Stone

Michael A Davis

A medical device incorporating magnetic material is introduced into the body of a patient. A time varying magnetic field is generated externally of the patient's body and which is of sufficient strength to magnetically induce motion in the device, thereby causing the medical device to vibrate within the patient's body. The frequency and the amplitude of the magnetic field oscillations can be continuously varied to control the vibrations induced in the medical device.

Apparatus and method for inducing vibrations in a living body

An apparatus for treatment of body tissue includes a treatment apparatus configured to be inserted into a patient. The treatment apparatus has a distal portion, a distal end, a proximal portion and an axis. An ultrasound transducer is positioned at the distal portion of the treatment apparatus. The ultrasound transducer includes a distal ultrasound energy delivery surface and a proximal ultrasound energy delivery surface. An ultrasound energy attenuator member is positioned adjacent to the proximal ultrasound energy delivery surface and is made of a material to at least partially attenuate ultrasound energy from the proximal ultrasound energy delivery surface.

Ultrasound device for axial ranging

A method of treatment by ultrasound comprises providing a first, ultrasound field intensity-to-voltage transducer sized for insertion into the vicinity of a treatment site and a second ultrasound treatment transducer. The free field intensities created by the second transducer in response to various second transducer exciting signal levels are determined. The first transducer outputs in the free field in response to various second transducer exciting signal levels are also determined. The first transducer is inserted into the vicinity of the treatment site, and the second transducer is positioned to create an ultrasound field at the treatment site. The distance from the second transducer to the first transducer is determined. An exciting signal is applied to the second transducer. The output of the first transducer is determined. The level of the exciting signal applied to the second transducer, the determined distance and the first transducer output are employed to determine the attenuation coefficient of the tissues between the second transducer and the first transducer.

Ultrasound intensity determining method and apparatus

A treatment tool such as a catheter, MIS or other surgical tool apparatus for placement within a heart chamber, organ aperture or other body opening and axial ranging therein, the apparatus particularly adapted for laser-assisted percutaneous transmyocardial revascularization (MTR). At the distal end of the tool is an annular ultrasound transducer with associated structure, positioned to transmit ultrasound signals substantially axially aligned with the axis of the treatment tool to the cardiovascular tissue, the transducer further receiving returning signals from the cardiovascular tissue to be treated. In a preferred embodiment, the transducer comprises a piezoelectric crystal material. The transducer assembly is attached to the distal tip of the tool such that a laser delivery means or other functional device can be extended through the lumen of the tool and the annular ultrasound transducer. In a preferred embodiment, the invention is a modular ultrasound device capable of being detachably attached to a steerable catheter, MIS or other surgical tool apparatus. The system also comprises a signal interface extending from the ultrasound transducer and signal processing component operatively connected to the signal interface for real time determination of at least one boundary surface of cardiovascular tissue relative to one or more positions of the distal tip of the treatment tool. A method of delivering laser energy to tissue is disclosed, the method including the steps of positioning the firing tip of a laser delivery means adjacent the front surface of the tissue, delivering laser energy to the tissue, transmitting ultrasound energy to the tissue, receiving ultrasound signals reflected from at least the rear surface of the tissue, and determining the distance betwveen the firing tip of the laser delivery means and the rear surface of the tissue. In a preferred embodiment, the method includes quantitative determination of the contractility or motion of the beating heart, such that changes in the depth of tissue can be used to control the channel depth or other treatment parameters. Retrolasing can also be achieved by mechanically piercing the tissue to a determined depth based on axial ranging measurements, and retracting the treatment tool while simultaneously delivering laser energy therefrom.

A transducer for use in a localization and therapeutic ultrasound system. The transducer of the present invention includes multiple elements that are driven separately. The elements operate together to focus a continuous wave ultrasound beam at a focal zone that is at a variable distance from the elements. The transducer includes a mechanism to adjust the focal distance so that the focal zone may be moved to multiple depths.

Annular array transducer

A spectral wavelength discrimination system and method for using are provided which allows the wavelength of a beam of radiation to be accurately determined using compact inexpensive optics and electronics. The system is particularly useful for identifying the emission wavelength of a multi-component marker system which includes a plurality of components having different wavelength ranges. The system comprises a wavelength selective beamsplitter, termed a Linear Wavelength Filter, that directs predetermined fractions of the beam at each wavelength into each of two output beams. The intensities of these output beams are measured. The measurements and selected system parameters, including the beamsplitter spectral characteristics and the detector sensitivity characteristics are used in a special algorithm for performing Fourier based wavelength-dispersive analysis. The unique solution of the Fourier based analysis is the wavelength of the beam of radiation. The system employs various optical components and structures to achieve the desired spatial resolution and sensitivity. Multiple channel devices and other special configurations are also described.

Spectral wavelength discrimination system and method for using

A schlieren imaging system provides quantitative images suitable for testing medical equipment. One embodiment includes precision optics which form an image of a volume of a medium through which an ultrasonic acoustic wave propagates. A spatial filter passes diffracted light but blocks other light. A camera forms an image of the medium from the diffracted light so that regions of the medium which diffract light have higher light intensity in the image. From image intensities, a processor determines acoustic pressures or intensities, typically as a value indicating an integral of the acoustic pressure or intensity along an optical path through the volume. Integrated pressure is determined from a look-up table which relates predicted light intensity to pressure values which cause the predicted light intensity. The system is calibrated by forming an image of a reference ultrasonic acoustic wave and determining a relation between the image intensities and predicted intensities. The system may include a timing circuit which periodically activates and deactivates a transducer and causes emission of synchronized pulses of light. The pulses of light are synchronized with a selected delay after activations of the transducer, so that an image is formed which shows an ultrasonic acoustic wave that has evolved during the delay.

Apparatus for quantitative measurements of ultrasonic wave power

Growing community of inventors

Sunnyvale, CA, United States of America

Claudio I Zanelli