University of Florida Research Foundation Inc

Claudio F Gonzalez

Graciela Liliana Lorca

A composition is provided herein, including microvesicles (MVs) isolated from a naturally occurring probioticsp. wherein the MVs are packaged in a capsule, emulsion, or tablet such that the packaged MVs are protected in a gastrointestinal tract for transport to an intestine of a subject. In another embodiment, a method for treating Type-1 diabetes including orally administering to a diabetic or pre-diabetic subject, or a subject at risk for becoming pre-diabetic or diabetic, a composition comprising an effective amount of microvesicles isolated from a naturally occurring probiotic strain comprising asp.i. In still a further embodiment, of improving immune function in a subject, comprising administering to the subject, the composition comprising an effective amount of microvesicles isolated from a naturally occurring probioticsp.

Mechanistic bacterial efector to prevent apoptosis of human beta cells

The subject invention provides compositions for promoting good health. Specifically, the subject composition can be used for alleviating symptoms of indigestion, abdominal pain, and cephalic syndrome, including in healthy subjects. In preferred embodiments, the compositions comprise an effective amount of one or moreisolates. Preferably, the bacteria used as an active ingredient in the compositions of the subject invention are of theN6.2 strain. The subject invention also provides methods for alleviating symptoms of indigestion, abdominal pain, and cephalic syndrome. These methods comprise the administration of a composition of the subject invention, wherein the composition preferably comprises an effective amount of one or moreisolates. Even more preferably, the subject method utilizes an effective amount ofN6.2.

Lactobacillus supplement for promoting gastric and immune health

A composition is provided herein directed to a mixture of one or moresp. and a phenolic compound. In a specific embodiment, disclosed is a/phenol mixture that has been lyophilized to form a/phenol lyophilized mixture. The/phenol mixture of/phenol lyophilized mixture may be packaged in a capsule, emulsion, or tablet such that theare protected in a gastrointestinal tract for transport to an intestine of a subject. In another embodiment, a method for treating Type-1 diabetes including orally administering to a diabetic or pre-diabetic subject, or a subject at risk for becoming pre-diabetic or diabetic, a composition comprising an effective amount of/phenol mixture or lyophilized mixture. In still a further embodiment, of improving immune function in a subject, comprising administering to the subject, the composition comprising an effective amount of/phenol mixture or lyophilized mixture.

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Gainesville, FL, United States of America

Claudio F Gonzalez