Lonza Inc.

Lonza Solutions Ag

Arxada Ag

Claudio Arnold

Christoph Taeschler

Christian Schnider

Stefan Tille

Ulrich Mayerhoeffer

Philipp Studer

Michael Bittel

Rolf Kalbermatten

Simon Kessler

Stefan Garms

Manuel Favre

Guy Raboud

Kilian Schnydrig

Martin Venetz

Christophe Girard

Thomas Eggel

The invention discloses a method for the preparation of 2-chloro acetoacetic acid amide or ester by a reaction of acetoacetic acid amide or ester with trichloroisocyanuric acid in the presence of amylene and in the solvent acetone.

Method for preparation of 2-chloroacetoacetic acid amide and ester

The invention discloses a method for the continuous preparation of n-butyl nitrite with a low content of n-butanol comprising the reaction of n-butanol, an acid and NaNOin a continuous way, in which the n-butanol, an acid and NaNOare mixed in a mixing device which provides for a pressure drop of at least 1 bar; the acid is selected from the group consisting of HCI, HSO, formic acid, methanesulfonic acid, and mixtures thereof; and the amount of HCI is at least 1.02 molar equivalent based on the molar amount of n-butanol.

Method for preparation of n-butyl nitrite

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Brig-Glis, Switzerland

Claudio Arnold