Cryocath Technologies Inc.

Medtronic Cryocath LP

Claudia Lückge

John W Lehmann

Jean-Pierre Lalonde

Dan Wittenberger

Domenic N Santoianni

Daniel Nahon

Cristian Petre

Fredric L Milder

Leonilda Capuano

Marwan Abboud

Philippe Marchand

Robert A Martin

Jean-Luc Pageard

Miriam Lane

Johnny Al Asmar

David Holtan

Abderrahim Benrabah

Ken Chen

Teresa Ann Mihalik

Steven G Arless

Michael J Urick

Kenneth A Spector

Willard W Hennemann

Patrick Chauvet

Jean-Pierre LaLonde

A cryogenic catheter includes an elongate, contiguous, thermally-transmissive region coupled to the catheter, the thermally-transmissive region being sufficiently flexible to change from a linear configuration to an arcuate configuration. The thermally-transmissive region may include a plurality of interconnected thermally-transmissive segments that are generally cylindrical in shape. The cryogenic catheter may be in fluid communication with a fluid source, and may include one or more fluid injection tubes. Further, an injection tube may be slidably disposed within the catheter so that the injection tube is longitudinally movable relative to an outer surface of the catheter. The cryogenic catheter may also be in communication with a controller programmed to regulate delivery of a cryogenic fluid from the fluid source to the medical device.

Cryosurgical catheter

A method is disclosed for treating an aneurysm or vascular defect by cooling a target tissue region of the aneurysm or vascular defect to a temperature below body temperature for a preselected time period. The method entails thickening, strengthening, or increasing the density of a blood vessel wall by cooling the blood vessel wall with a cryogenically cooled device. The method also includes irradiating the inner wall of a blood vessel around an aneurysm or vascular defect with various forms of energy to delay or halt aneurysm or vascular defect formation. An energy-emitting element is disposed on the distal end portion of a catheter device to be disposed proximate the aneurysm. Various forms of energy, including visible light energy, laser light energy, ultrasound, microwave and radiofrequency sources may be used to irradiate and treat the aneurysm. In addition, the method may include irradiating a tissue site concomitantly with other treatments, including the delivery of vaso-occlusive compounds, mechanical intravascular devices, or an endovascular graft to the target tissue region.

Method for treatment of aneurysms

An elongated catheter device with a distal balloon assembly is adapted for endovascular insertion. Coolant injected through the device may, in different embodiments, directly cool tissue contacting the balloon, or may cool a separate internal chamber. In the first case, the coolant also inflates the balloon, and spent coolant is returned to the handle via a return passage extending through the body of the catheter. Plural balloons may be provided, wherein a secondary outer balloon surrounds a primary inner balloon, the primary balloon being filled with coolant and acting as the cooling chamber, the secondary balloon being coupled to a vacuum return lumen to serve as a robust leak containment device and thermal insulator around the cooling chamber. Various configurations, such as surface modification of the balloon interface, or placement of particles, coatings, or expandable meshes or coils in the balloon interface, may be employed to achieve this function.

Endovascular cryotreatment catheter

A cryogenic catheter includes an outer flexible member having at least one cryogenic fluid path through the flexible member. The at least one fluid path is defined by a plurality of flexible members disposed within the outer flexible member.

A cryosurgical system including a housing having a front portion and a rear portion. The front portion and rear portion are connectable to support a fluid supply. A control unit attached to the front portion, and has a regulator assembly connecting the fluid supply to the control unit. A medical device is connected to the control unit, the medical device including a handle, a shaft, and a thermally-transmissive region. The handle, the shaft, and the thermally-transmissive region defining a fluid pathway through the handle, shaft, and thermally-transmissive region. The shaft is malleable to retain a first shape until manipulated to a second shape.

Coolant injection

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Ile Perrot, Canada

Claudia Lückge