Alexander Wang Incorporated

Icahn School of Medicine at Mount Sinai

Claudia Kim

Alexander Wang

Ming-Ming Zhou

Matthew Galsky

Sudeh Izadmehr

Chunyan Ren

A genus of bicyclic inhibitors of CBX chromodomains is disclosed. The compounds are of the following genus: in which A, E, and G represent carbon or nitrogen such that the compounds are indoles or benzimidazoles. A particular subgenus of 1,3-disubstituted-1,3-dihydro-2H-benzo[d]imidazol-2-imines is of the general formula: The compounds inhibit CBX proteins.

Bicyclic inhibitors of CBX chromodomains

Bag with skeletal corners

Bag with feet

A shopper bag having a substantially rectangular opening at the top and closed bottom for articles to be placed into and removed from the bag. The bag includes a front and opposed back panel with a closed rectangular bottom to provide the rectangular mouth opening at the top. A first handle is mounted on one panel at the opening and an horizontal slit is formed in the opposed panel so that the upper portion of the slit and the first handle can be used to lift the bag. A larger collar is formed on the same side as the first handle. The collar is configured to fit through, the horizontal slit opening to draw both opposed panels together at the mouth and allow a user to place the collar on one's neck or shoulder to carry the bag.

Shopper bag

Bag with corners

Growing community of inventors

New York, NY, United States of America

Claudia Kim