Gruenenthal Gmbh

Leiden University

Claudia Katharina Puetz

Werner Guenter Englberger

Oswald K Zimmer

Babette-Yvonne Koegel

Wolfgang Werner Strassburger

Bernd Sundermann

Matthias Gerlach

Corinna Sundermann

Michael Haurand

Boris Chizh

Helmut Heinrich Buschmann

Klaus Schiene

Hagen-Heinrich Hennies

Achim Kless

Derek John Saunders

Petra Bloms-Funke

Ivars Graudums

Dagmar Kaulartz

Adriaan Pieter Ijzerman

Heinz Uragg

Carsten Griebel

Wolfgang Werner Alfred Strassburger

Reynier Tromp

Sabine Reinardy

Jacobien Von Frijtag Drabbe Kuenzel

Gero Gaube

D Enders

Sulfonylguanidine compounds corresponding to the tautomeric formulas I and Ia, a method for producing them, pharmaceutical compositions containing them, and methods of using them to prepare medicaments and for treating various medical conditions. The sulfonylguanidine compounds have an affinity for the gabapentin binding site and can be used to treat conditions such as pain, epilepsy, migraine and others.

Sulfonylguanidine compounds and pharmaceutical uses thereof

Saturated and unsaturated heteroarylcycloalkylmethyl-amine compounds corresponding to formula I, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of saturated and unsaturated heteroarylcycloalkylmethyl-amines for the preparation of pharmaceutical formulations. pharmaceutical formulations and related methods of treatment or prophylaxis of certain condition, especially depression and/or pain, are also disclosed.

Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants

Analogs or derivatives of nitrobenzylthioinosine compounds. The use of these new analogs of nitrobenzylthioinosine and methods for the treatment of pain and various other indications using these analogs of nitrobenzylthioinosine as well as pharmaceutical compositions including analogs of nitrobenzylthioinosine.

Analogs of nitrobenzylthioinosine

Aminomethyl-phenyl-cyclohexanone derivatives of formula I or Ia,their diastereomers, enantiomers and salts formed with a physiologically tolerated acid. Also disclosed are processes for preparing the same, pharmaceutical compositions comprising the same, and methods of using the same for the treatment of pain, inflammatory reaction, allergic reactions, depression, drug abuse, alcohol abuse, gastritis, cardiovascular disease, respiratory tract disease, coughing, mental illness, epilepsy, urinary incontinence, itching, and diarrhoea.

Aminomethyl-phenyl-cyclohexanone derivatives

Thio-alpha-amino acids of general formula (I), wherein R, Rand Rhave the meanings given in the description, methods for producing them, and medicaments containing these compounds. The invention also provides methods for treating pain and other diseases using the pharmaceutical compositions comprising the thioamino acids.

&#x3b2;-thioamino acids

Substituted aminomethyl-phenyl-cyclohexane derivatives

This invention relates to intermediates in the preparation of acridin derivatives of general formula

Acridin derivatives

This invention relates to acridin derivatives of general formula ##STR1## or pharmaceutically acceptable salts thereof, to a method of producing them and to their use as analgesics.

This invention relates to substituted heterocyclic benzocycloalkenes of general formula I or pharmaceutically acceptable salts thereof, to a method of producing them and to their use as analgesics.

Substituted heterocyclic benzocycloalkenes and the use thereof as

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Dueren, Germany

Claudia Katharina Puetz