Symrise Ag

Claudia Gömann

Heiko Oertling

Gabriele Vielhaber

Rahim Brodhage

Imke Meyer

Oskar Koch

Martina Herrmann

Michael Krohn

Dominik Stuhlmann

Holger Zinke

Antje Köhler

Nicole Titze

Karin Schaper

Nadine Hillebrand

Helko Oertling

Marc Vom Ende

The invention relates generally to new compounds of formula (I), wherein R, R', R, R&#x2032;, R, R&#x2032;, RR&#x2032;, R, R&#x2032;, R, Rare independently of one another and denote hydrogen, hydroxyl, Cto C-alkyl group or Rand Rform together a C5-C6 ring system, and wherein n=0, 1, 2, 3, or 4. Moreover, the invention relates to the use of one or more compounds of formula (I) in cosmetic or pharmaceutical compositions, which are preferably dermatological compositions and are preferably used topically. 

Succinate derivatives

The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as skin and/or hair lightening (whitening) actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition for lightening human skin and/or hair and to novel compounds of formula (I) wherein A denotes wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4 -alkenyl,

Cyclohexyl carbamate compounds as skin and/or hair lightening actives

The present invention primarily relates to the use of trans-tert-butyl cyclohexanol as skin irritation-reducing agent as well as compositions (formulations) having a skin irritation-reducing action comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent.

Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent

The present invention relates to the cosmetic, dermatological or pharmaceutical (therapeutic) use of compounds of formula (I) or a cosmetically acceptable salt of a compound of formula (I) or a mixture containing two or more of these compounds or the salts thereof wherein The invention further relates to compositions and cosmetic, dermatological or pharmaceutical preparations (compositions) comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition for lightening human skin and/or hair and to certain novel compounds of formula (I).

Menthyl carbamate compounds as skin and/or hair lightening actives

Compounds and methods of using of compounds or mixtures thereof, as fragrance and/or flavoring material or as fragrance and/or flavoring material mixture, new fragrance and/or flavoring material mixtures, new perfumed and/or flavored articles, and new, particularly advantageous compounds and mixtures to be used are described.

Dihydrobenzofuran derivatives as fragrance and/or flavoring materials

The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and novel compounds of formula (I) wherein A denotes wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4-alkenyl,wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms,B denotes NRR, whereinRdenotes hydrogen or an organic radical having 1 to 14 carbon atoms,Rdenotes an organic radical having 1 to 14 carbon atoms, andwherein optionally Rand Rare covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.

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Golmbach-Warbsen, Germany

Claudia Gömann