Ludwig Institute for Cancer Research Limited

Claude Wildmann

Thierry R Boon-Falleur

Pierre Van Der Bruggen

Pierre G Coulie

Jean-Christophe Renauld

Pascale Bo{haeck Over (e)}l

Pascale Boel

Jean-Pierre Szikora

Pascale Bo&euml;l

Peptides which satisfy the formula of SEQ ID NO: 10 bind to HLA-Cw*1601 molecules, and stimulate proliferation of cytolytic T cells. Examples of such peptides are those set forth in SEQ ID NOS: 4 and 5.

METHOD FOR IDENTIFYING INDIVIDUALS SUFFERING FROM A CELLULAR ABNORMALITY SOME OF WHOSE ABNORMAL CELLS PRESENT COMPLEXES OF HLA-CW 1601/MAGE-1 DERIVED PEPTIDES, AND METHODS FOR TREATING SAID INDIVIDUALS

A family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as BAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as BAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigen precursor molecules are described.

Method for treating subjects by using BAGE tumor rejection antigen precursors or tumor rejection antigens

Isolated nucleic acid molecule encoding peptides which form complexes with MHC molecules HLA-Cw*1601 and uses thereof

Methods for determining complexes of tumor rejection antigens and

Isolated nucleic acid molecule encoding peptides which form complexes

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Brussels, Belgium

Claude Wildmann