Laboratoires D'hygiene Et De Dietetique

Crossject

Iomed, Inc.

Laboratoires D'hygiene Et De Dietetique (l.h.d.)

Societeanonyme Dite: Labratoires D'hygiene Et De Dietetique

Societe Anonyme Dite: Laboratoires D'hygiene Societe Anonyme Dite: Et De

Claude Mikler

Michael Paton

Patrick Alexandre

Eric Teillaud

Bernard Brouquieres

Paul J Reilly

Philippe Millot

Bruno Bevan

Daniel Dhuique-Mayer

Alain Navelier

Laurent Liorzou

Louis Simonet

Chantal Bon-Lapillonne

Carole Rossi

Daniel Esteve

Pascal Andre Nicolas Muller

Eric Thomas McAdams

Dao Min Zhou

Brigitte Cagnon

Pierre Brunet

The technical field of the invention is that of needleless syringes used for intradermal, subcutaneous or intramuscular injections of active principle for therapeutic purposes. More particularly, the invention concerns a needleless syringe () comprising a propelling system, the active principle and an application guide (), mainly characterised in that the propelling system consists of an impact wave generating device () and the active principle is arranged in at least a blind cavity () of the downstream surface () of a barrier () extended by the application guide (). Thus, the active principle is expelled in the form of streamlined jets, driven at very high speed.

Needleless syringe operating with an impact wave generator through a wall

The invention concerns the field of needleless syringes for injecting an active principle for therapeutic purposes. More particularly, it concerns a needleless syringe for injecting an active principle () initially set between an injector () comprising at least an injection nozzle, said injector being contacted with the skin, and a wall () mobile under the effect of a propelling system () pressurizing and expelling the active principle through the injector located at the syringe downstream end (). In order to produce nozzles in a considerable injector thickness and to control the jet coherence distance, said injector () comprises at least two elements () whereof the contact surfaces (') are oriented towards the skin, at least a groove () forming an injection nozzle in the assembly of said elements.

Needleless syringe comprising an injector with nested elements

Electrode for the transferring an electric current through a patient's skin

The invention concerns the technical field of needleless syringes for injecting an active principle through the skin. More particularly, the invention concerns a needleless syringe provided with a piezoelectric crystal and a triggering device comprising a triggering member and impacting means and, on a triggering device particularly adapted to needleless syringes. The invention is mainly characterized in that the impacting means comprises a latch maintained under elastic stress by being blocked against a stop element and the triggering member is capable of moving the latch to release it, so that it is urged to strike the piezoelectric crystal. Then, the crystal produces an electric arc designed to initiate a pyrotechnic charge whereof the combustion gases will help to expel the active principle contained in the syringe.

Needless syringe provided with a piezoelectric triggering system

A miniature valve for filling the reservoir of an apparatus for the transdermal administration of a medicine including a) a substrate, b) a fuel charge arranged on the substrate opposite the passage to be opened through it, and c) an electric resistor placed in contact with the fuel charge so that the supply of this resistor with a predetermined electric energy ensures the combustion of the charge and the opening of the passage by local rupture of the substrate under the pressure of the fuel gases of the charge. The device is useful for filling a medicine reservoir for the transdermal administration medicine aided by inophoresis.

Miniature valve for filling the reservoir of an apparatus for the transdermal administration of medicine

Transdermal matrix system

This invention is concerned with a new transdermal matrix system for the percutaneous administration of a hormone, said matrix system, which has a support and a self-adhesive matrix, comprising a matrix containing:

Styrene-isoprene-styrene copolymer-based transdermal matrix system for

The device comprises a switched-mode power supply (1) equipped with an electronic switching member (T.sub.1), the closing of which controls the power supply to an inductor (L.sub.1) which discharges, when the member reopens, into a capacitor (C.sub.1) at the terminals of which the output voltage of the device appears, characterized in that it comprises (a) storage means for recording a sequence of image numbers of successive segments of the predetermined waveform, (b) a clocked digital counter (2) and (c) means (3) for successively loading this counter (2) with each of the numbers of this sequence considered as a bound of the count performed by the counter (2), the latter cyclically controlling the closing of the switching member (T.sub.1) for a predetermined time interval, each time the count performed reaches the limit thus fixed.

Transdermal drug delivery device with waveshape generator

Applicator for ionophoretic transcutaneous delivery of drugs

Device for generating an electrical voltage of predetermined waveform,

Applicator for electrophoretic transcutaneous delivery of drugs

Growing community of inventors

Dijon, France

Claude Mikler