Proyecto De Biomedicina Cima, S.l.

Claude Leclerc

Jesus Prieto Valtuena

Juan Jose Lasarte Sagastibelza

Marta Gorraiz Ayala

This invention relates to the use of a polypeptide in the production of an immunostimulatory agent, said polypeptide comprising a sequence corresponding to the EDA domain of fibronectin, a fragment of the EDA domain which can bind to TLR4 or a variant of said EDA domain or a fragment which can bind to TLR4 and which has a homology of more than 70% with any form or natural fragment of the EDA domain. The invention also relates to the production methods and applications of said agent.

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Navarra, Spain

Claude Leclerc