Prolabo

Rhone-poulenc Recherches

Claude Guillemin

Christian Mayen

Jean-Pierre Vasseur

Jean Lissot

This invention relates to a process and installation for on-line analysis of a liquid product by liquid phase chromatography, the device for carrying out the process including a sampling and treatment probe disposed within the product and a chromatograph associated with the probe. An eluate detector disposed remote from the chromatograph and a monitoring unit takes into account the variations of appearance of a noteworthy peak with respect to the same peaks of an earlier chromatogram.

Process and installation for on-line analysis of a liquid product by

For a fluid chromatography apparatus including a precolumn and an analytical column, a device is provided with means for operably connecting said precolumn and column, said connecting means comprising a body member provided with support surfaces for a column inlet and a precolumn outlet, and said body member including a plurality of passages adapted to independently functionally interconnect said precolumn outlet and said column inlet with each other, and individually independently with fluid inlet and/or outlet means, either internally or externally.

Device for column chromatography apparatus

An improved device/apparatus for sweeping and injecting a sample and at least one standard into the separation column of a fluid-phase chromatograph, including (i) means for securing same to the inlet of such separation column, (ii) a supply inlet for a stream of carrier medium and means for directing said stream to said separation column, (iii) dividing means in said device for dividing said stream into primary and secondary streams, (iv) distributing means for directing said primary stream to said separation column and distributing said primary stream over the inlet area of said column, (v) means for directing said secondary stream axially into said separation column inlet, and (vi) means for introducing a sample into said secondary stream, the improvement which comprises (vii) means for introducing at least one standard also into said secondary stream.

Sample/standard injection head for fluid-phase chromatograph

In this device, for sweeping and injecting samples into the separation column of a chromatography apparatus, the separation column is secured to an opening connecting with a conduit which feeds a stream of carrier liquid to the device. The device subdivides a stream of carrier liquid into a primary stream and a secondary stream and feeds the primary stream over the entire cross section of the entrance to a separation column. Simultaneously feed of the secondary stream axially to the entrance of the separation column is performed while introducing the sample into the secondary stream. The device is usable particularly in liquid-phase chromatography.

Sample sweeping and injection device for chromatography apparatus

A safety device for distributing the carrier liquid of a chromatography apparatus having a carrier liquid source, a carrier liquid reservoir provided with an entrance and an outlet, an overflow conduit, a conduit for conveying the carrier liquid toward the chromatography apparatus, and three interdependently controlled valves respectively located between the exit of the reservoir and the overflow conduit, between the entrance of the reservoir and the carrier liquid source, and between the carrier gas source and the reservoir exit. The device is usable for distributing the carrier liquid of a liquid-phase chromatography apparatus wherein the carrier liquid is pushed by a carrier gas.

Safety device for chromatography apparatus

A separation column is removably affixed within a column chromatography apparatus by means of a column engaging member, e.g., a concentric tube, and by securing a dispensing head of the apparatus to such member and engaged column via substantially axial compressive strength applied through said column engaging member.

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Paris, France

Claude Guillemin