United States of America As Represented by the Secretary of the Air Force

Claude C Grigsby

Sean W Harshman

Anthony V Qualley

Rhonda L Pitsch

Darrin K Ott

Jeffrey B Phillips

Brian A Geier

Nicole M Schaeublin

Jennifer A Martin

A biomarker diagnostic system includes a sensor to collect a sweat sample from a biological subject; a processor operatively connected to the sensor, wherein the processor is configured to perform metabolic and proteomic profiling of biomarkers in the sweat sample. The metabolic and proteomic profile is compared to a predetermined profile of the biomarkers and to determine a physiological status of the biomarkers. The system further includes a feedback unit operatively coupled to the sensor and the processor and configured to output physiological performance data based on the physiological status.

Identification, quantitation and analysis of unique biomarkers in sweat

A method of detecting hypoxia. Detecting hypoxia includes detecting, in exhaled breath, at least one indicator for hypoxia. The at least one indicator is selected from the group consisting of pentanal, 2-pentanone, 2-hexanone, 2-heptanone, 2-cyclopenten-1-one, and 4-butyrolactone.

Exhaled breath hypoxia biomarkers

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Beavercreek, OH, United States of America

Claude C Grigsby