Miles Inc.

Bayer Corporation

Clarence L Hancock

Lawrence J Daher

Thomas A Alexander

Donald L Peterson

Gerald Gold

Hydrolyzed gelatin has been found to provide an improvement in taste and mouthfeel when incorporated in small amounts into chewable tablets containing ingredients requiring taste masking. Medicinals and nutritional supplements may now be prepared as chewables for those who find tablets difficult to swallow, for example children and older adults, or for those who prefer the convenience. There is a particularly large improvement in the taste and mouthfeel of chewables incorporating magaldrate and/or calcium carbonate.

Hydrolyzed gelatin as a flavor enhancer in a chewable tablet

Hydrolyzed gelatin as a flavor enhancer in a chewable table

The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rapid disintegration or dispersion are important factors. It is useful for tablets containing ingredients which are difficult to compress and is particularly useful for formulating swallowable tablets of a single non-soluble ingredient such as calcium carbonate. Disintegration times are markedly decreased.

Method of preparing oral dosage forms with a granulating composition

Granulating composition and method

Growing community of inventors

Edwardsburg, MI, United States of America

Clarence L Hancock