Ucb Pharma, S.a.

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Katholieke Universiteit Leuven, Ku Leuven R&d

Ucb Biopharma Sprl

Claire Louise Kulisa

Daniel Christopher Brookings

James Thomas Reuberson

Daniel James Ford

Anant Ramrao Ghawalkar

Judi Charlotte Neuss

Richard Jeremy Franklin

Rikki Peter Alexander

Bart Vanderhoydonck

George Martin Buckley

Jean Herman

Qiuya Huang

Thierry Louat

Pavandeep Singh Aujla

Mark James Batchelor

James Petrie Turner

Karen Viviane Crepy

Compounds of formula (I) i.e. monocyclic or bicyclic diamine-substituted thieno[2,3-d]pyrimidine and isothiazolo[5,4-d]pyrimidine derivatives substituted by an optionally substituted oxazolin-2-yl moiety, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection. 

Therapeutically active oxazoline derivatives

A series of monocyclic or bicyclic diamine-substituted thieno[2,3-d]pyrimidine and isothiazolo[5,4-d]pyrimidine derivatives are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection.

Therapeutically active fused pyrimidine derivatives

A series of thiazolo[5,4-d]pyrimidine derivatives of formula (I) or an N-oxide thereof, or a pharmaceutically acceptable salt or solvate thereof: (I) Q represents a group of formula (Qa), (Qb), (Qc), (Qd) or (Qe) are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection. 

Therapeutically active thiazolo-pyrimidine derivatives

A series of 5,6-dihydro-1,3-benzothiazol-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PD kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

Fused thiazole derivatives as kinase inhibitors

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Slough, United Kingdom

Claire Louise Kulisa