Globeimmune, Inc.

Core-tech, Inc.

Endo Pharmaceuticals Colorado, Inc.

Claire Coeshott

Thomas H King

David Apelian

Zhimin Guo

John C Cheronis

Gary Joseph Rosenthal

Timothy C Rodell

Yingnian Lu

Wren Henderson Schauer

Joan P Blonder

Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.

Compositions and methods for the treatment or prevention of hepatitis B virus infection

Yeast-based therapeutic for chronic hepatitis B infection

Disclosed are fusion proteins, recombinant nucleic acid molecules, and therapeutic compositions, including yeast-based immunotherapy compositions, for use in the diagnosis, prevention and treatment of adenovirus-36 (Ad-36) infection and sequela thereof.

Compositions and methods for the treatment or prevention of human adenovirus-36 infection

The present invention provides an immunogen composition and methods for using the same for the development of immunity, and particularly at mucosal sites in a mammal, thereby providing immunity at the site of entry for many major pathogenic organisms and also systemic immunity. The immunogen composition includes an antigen, a biocompatible polymer, and a liquid vehicle, with the biocompatible polymer and liquid vehicle being present in such proportions and interacting in such a way that the immunogen composition exhibits reverse-thermal viscosity behaviour. A delivery vehicle composition including a drug other than an antigen is also provided. Methods are provided for delivering the compositions of the invention to a host.

Delivery vehicle composition and methods for delivering antigens and other drugs

The present invention relates to immunogenic constructs capable of eliciting an IgG antibody response in a host in the absence of adjuvant.

Immunogenic constructs comprising b-cell and t-cell epitopes on common

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Denver, CO, United States of America

Claire Coeshott