Children's Medical Center Corporation

Ganna Bio, Inc.

Ciaran Lawlor

Carolyn Ruth Bertozzi

Brian Goodman

Richard D Cummings

Namita Bisaria

Ryan A Flynn

Mohui Wei

The present disclosure relates to glycan-modified nucleic acids, including short interfering RNA molecules. The glycan-modified nucleic acids include an oligosaccharide moiety that is bond to the nucleic acid and that contains a multiple antennary complex type N-glycan. The disclosure also relates to pharmaceutical compositions containing such glycan-modified nucleic acids, and methods for making and using such glycan-modified nucleic acids.

Glycan modified short interfering RNA

Growing community of inventors

Milton, MA, United States of America

Ciaran Lawlor