National University of Singapore

Massachusetts Institute of Technology

Other

Shanghai Jiao Tong University

Chwee Teck Lim

Jongyoon Han

Wang Xi

Joo Chuan Yeo

Fook Chiong Cheong

Guofeng Guan

Han Wei Hou

Krystyn J Van Vliet

Lidan Wu

Ali Asgar Bhagat

Wong Cheng Lee

Majid Ebrahimi Warkiani

Longteng Yu

Xiaobo Gong

Victor Phyau Wui Shim

Kah Ping Andy Tay

Kenry

Fang Kong

Ramesh Ramji

A soft, flexible microtube sensor and associated method of sensing force are described. A liquid metallic alloy is sealed within a microtube as thin as a strand of human hair to form the physical force sensing mechanism. The sensor is hardly distinguishable with the naked eye, and can be used for the continuous biomonitoring of physiological signals, such as unobtrusive pulse monitoring. Also described is a method of fabricating the microtube sensor and wearable devices incorporating one or more microtube sensors.

Microtube sensor for physiological monitoring

The present invention relates to a flexible polymer-based microtube having an inner diameter of about 4 &#x3bc;m to about 1000 &#x3bc;m and a variable outer diameter, wherein the cross-sectional shape of the microtube can be, for instance, circular, rectangular, square, triangular, elliptical, star or irregular. The present invention also relates to a method of making the flexible microtube and devices incorporating the flexible microtube.

Versatile, flexible and biocompatible elastomeric microtubes

A system for intra-operative blood salvage autotransfusion is provided. The system comprises at least one inlet configured to receive whole blood of a patient; at least one curvilinear microchannel in fluid flow connection with the at least one inlet, the at least one curvilinear microchannel being adapted to isolate circulating tumor cells in the whole blood, based on cell size, along at least one portion of a cross-section of the at least one curvilinear microchannel; and at least two outlets in fluid flow connection with the at least one curvilinear microchannel, at least one outlet of the at least two outlets being configured to flow the circulating tumor cells isolated from the whole blood, and at least one other outlet of the at least two outlets being configured to flow at least a portion of a remainder of the whole blood, cleansed of the isolated circulating tumor cells, for return to the patient.

System and method for inertial focusing microfiltration for intra-operative blood salvage autotransfusion

A resistive microfluidic pressure sensor is provided which comprises a first layer comprising a microfluidic channel with a carbon-based conductive liquid and a second layer comprising at least two electrodes, the at least two electrodes being adapted to measure resistance of the carbon-based conductive liquid upon deformation of the microfluidic channel as a result of a change in force applied on a surface of the sensor.

Resistive microfluidic pressure sensor

The disclosure relates to a method and device for detecting and quantifying biological molecules such as cell surface or intracellular ligands/receptors in a dynamic system with high sensitivity and specificity; the method of using such platform optionally in combination with an optical detection system and kits comprising the optical platform.

Assay device

A method of detecting one or more diseased blood cells in a blood sample includes introducing a blood sample into at least one inlet of a microfluidic device comprising one or more linear channels wherein each channel has a length and a cross-section of a height and a width defining an aspect ratio adapted to isolate diseased blood cells along at least one portion of the cross-section of the channel based on reduced deformability of diseased blood cells as compared to non-diseased blood cells, wherein diseased blood cells flow along a first portion of the channel to a first outlet and non-diseased blood cells flow along a second portion of the channel to a second outlet. The one or more channels can be adapted to isolate cells along portions of the cross-section of the channel based on cell size. In some embodiments, the one or more channels can be spiral channels.

Microfluidics sorter for cell detection and isolation

A drop tester ( ) including a gripper mechanism ( ) for holding a product ( ) to be tested, a guide track, a slider block ( ) which is mounted to slide along the guide track and advance the mechanism toward a target location ( ) and a release device ( ) for triggering release of the product from the mechanism to impact at the target location, characterised in that the gripper mechanism includes gripper arms ( ) coupled to the slider block, the gripper arms being rotatable relative to the slider block to enable the orientation of the product to be varied, relative to the target location. The slider block is preferably releasably coupled to a hoisting block ( ) which is positionable at a predetermined location along the guide track. More preferably, the gripper arms are pivotally mounted to a housing ( ) and coupled to a piston ( ) provided within the housing, the arms pivoting between a gripping position and a release position upon advancement of the piston through the housing.

Impact drop tester for portable consumer products

Growing community of inventors

Singapore, Singapore

Chwee Teck Lim