Shanghai Microport Cardioflow Medtech Co., Ltd.

Chunxia Zhao

Ming Yang

Guoming Chen

Yu Meng Li

Ming Liu

Yu Li

The present application relates to a cardiac valve prosthesis and a stent thereof. The stent comprises an inflow channel, an outflow channel, and a transitional area between the inflow channel and the outflow channel along an axial direction; the outflow channel comprises a cyclic structure and at least two convex structures extending along the axial direction; the at least two convex structures are respectively connected to the end of the cyclic structure distant from the transitional area; a restricted vacant area is formed between adjacent convex structures. The cardiac valve prosthesis and the stent thereof are not only suitable for multiple types of valve replacement, risks of injuries and operation costs are reduced for patients, and the influence of the stent to cardiac functions is minimized.

Cardiac valve prosthesis and stent thereof

A valve stent and a valve prosthesis. The valve stent is in the shape of a mesh tube, and has a compressed state and an expanded state. The valve stent includes an inflow tract structure, a transition tract structure, an outflow tract structure, and a barb structure. The transition tract structure has a fifth end portion, a sixth end portion, and a first middle section. In the expanded state, the diameters of the radial sections of the fifth end portion and the sixth end portion are greater than the diameter of the radial section of the first middle section of the transition tract structure. The outflow tract structure has a seventh end portion and an eighth end portion. The seventh end portion of the outflow tract structure is fixedly connected to the sixth end portion of the transition tract structure, and the eighth end portion is a free end. The barb structure is disposed on the transition tract structure and the outflow tract structure, and protrudes towards the outside of the transition tract structure and/or the outflow tract structure. The valve stent and the valve prosthesis can be stably anchored on natural valves.

Valve stent and valve prosthesis

A mitral valve prosthesis, a tricuspid valve prosthesis and a stent thereof. The stent is configured to support the heart valves of the mitral valve prosthesis and has a contracted configuration for delivery and an expanded configuration for deployment. The stent comprises, along its axial direction, an inflow section, a transition section and an outflow section, and the transition section is connected to the inflow section at one end and to the outflow section at the other end. When in the expanded configuration, the inflow section is located upstream of the outflow section with respect to the blood flow direction. The inflow section is less radially rigid than the outflow section and/or the transition section. Due to such a small radial rigidity, the inflow section can well adapt itself to the anatomy of the native mitral annulus. As a result, its pressure and interference on the aortic valve can be reduced, resulting in a significant decrease in the risk of leading to occlusion of the left ventricular outflow section. Additionally, during the release, the inflow section can adapt itself to changes in the diameter of the stent and thereby buffer radial deformation and axial displacement of the stent during its expansion, thus enhancing the release reliability.

Growing community of inventors

Shanghai, China

Chunxia Zhao