H. Lee Moffitt Cancer Center and Research Institute, Inc.

Chongqing Zein Pharmaceutical Co., Ltd

Chunwei Cheng

Rongshi Li

Yan Liu

Yong Qin

Hao Song

Said M Sebti

Marinopyrrole derivatives and methods for their synthesis and use are described herein. Novel cyclic and symmetric marinopyrroles with triazole substituents having antibacterial activity against resistant bacterial strains, such as MRSA are introduced. Also provided are methods of using the compounds for treating or preventing cancer and/or microbial infections.

Marinopyrrole derivatives and methods of making and using same

Symmetrical marinopyrrole derivatives are disclosed herein, as is a synthetic route for producing these compounds. Also disclosed are methods of using symmetrical marinopyrrole derivatives to treat bacterial pathogens, like MRSE, MSSA and MRSA.

Symmetrical marinopyrrole derivatives as potential antibiotic agents

Growing community of inventors

Zhumadian, China

Chunwei Cheng