Lifearc

Suzhou Yabao Pharmaceutical R&d Co., Ltd.

Chunjun Chu

Lin Zhu

Edward Giles Mciver

Ling Wu

Yan Xia

Yang Song

Justin Stephen Bryans

Yuanyuan Xu

Miao Liu

Provided are a substituted tricyclic heterocyclic compound of formula I or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt, ester or a prodrug thereof, a pharmaceutical composition including the same and uses thereof. The substituted tricyclic heterocyclic compounds and the pharmaceutical compositions comprising the compounds disclosed herein can be used for treating a disorder caused by at least one of cancer and neurodegenerative diseases. Further the compounds and the pharmaceutical compositions comprising the compounds disclosed herein can be also used for preventing or treating a disorder caused by, associated with or accompanied by any abnormal kinase activity. 

Substituted tricyclic heterocyclic compounds and use thereof

Growing community of inventors

Jiangsu, China

Chunjun Chu