Cornell University

Chunhui (Chris) Xu

Watt W Webb

Dimitre Gueorguiev Ouzounov

Douglas Scherr

Scott Howard

Minghan Chen

Demirhan Kobat

David Huland

Ke Wang

Guanghao Zhu

David R Rivera

James W Van Howe

Christopher M Brown

A microendoscope, and a microendoscopy method related to the microendoscope, each include a tube housing, where an end of the tube housing is shaped and finished to facilitate collection of light emitted from a sample when examined using the microendoscope. In addition, a catadioptric lens assembly, an endomicroscope that includes the catadioptric lens assembly and a microendoscopy method for microscopic analysis that uses the endomicroscope are predicated upon a second element and a third element within the catadioptric lens assembly that each has a dichroic coating. The placement of the dichroic coating on the second element and the third element provides for different magnification factors as a function of illumination wavelength when using the microendoscopy method.

Dual mode microendoscope concentrating light emission into ring area

An optical lens comprising a lens body that transmits light in an optical path there through, wherein the lens body consists of an anterior surface, a posterior surface, and a medium there between, further wherein one of the anterior surface and the posterior surface has a single curvature and the other of the anterior surface and the posterior surface has at least two optical zones each having a different curvature. An optical system, comprising a multi-photon endoscope having a distal end, and the optical lens disposed in the distal end. A method for obtaining an image of an object comprising providing the multi-photon endoscope, propagating light from the endoscope scanner one optical zone of the lens to focus the light at a focus location, and propagating light from the scanner through a different optical zones of the lens to focus the light at a different focus location.

Multi-focal optical component, optical system, and imaging method

Embodied is a two-color, fiber-delivered picosecond source for coherent Raman scattering (CRS) imaging. A wavelength tunable picosecond pump is generated by nonlinear spectral compression of a prechirped femtosecond pulse from a mode-locked titanium:sapphire (Ti:S) laser. A 1064-nm picosecond Stokes pulse is generated by an all-fiber time-lens source (or suitable alternative source) that is synchronized to the Ti:S laser. The pump and Stokes beams are combined in an optical fiber coupler, which serves not only as the delivery fiber but also as the nonlinear medium for spectral compression of the femtosecond pulse. CRS imaging of mouse skin is performed to demonstrate the practicality of this source.

Laser based apparatus, methods and applications

An optical scanner, scanner apparatus, or scanner assembly, which may be particularly advantageous for use in a multiphoton microscope, includes a first drivable bending component, a second drivable bending component mounted perpendicularly to the first component, and at least one optical waveguide coupled one or both of the first and second bending components, wherein the at least one optical waveguide provides both a propagation path for a multiphoton excitation radiation delivery between a light source and a target and a multiphoton-induced emission radiation delivery between the target and a detector. A GRIN relay lens. A multiphoton microscope incorporating the scanner and the GRIN relay lens.

Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods

Methods and systems for compensation of Self-Phase Modulationin fiber-based amplifier systems

Growing community of inventors

Ithaca, NY, United States of America

Chunhui (Chris) Xu