Kaohsiung Medical University

Chung-Yi Chen

Hui-Min David Wang

Zhi-Hong Wen

A-Mei Huang

Pei-Jung Lien

Yen-Hsu Chen

Yi-Ting Chou

Chien-Chih Chiu

Jih-Heng Li

Chiung-Hui Liu

Hsi-An Chen

Wei-Ru Lin

A method for improving tetracycline-resistance of, by providing a ginger compound combined with tetracycline to againstinfection, wherein the ginger compound comprises [6]-dehydrogingerdione, [6]-shogaol and [6]-gingerol or [10]-gingerol, [6]-shogaol and [6]-gingerol.

[object Object]

A method for promoting proliferation and/or migration of skin cells includes providing a composition containing a compound of formula (I) below; and administrating to the skin cells the composition. A method for improving wound healing in a subject includes providing a composition containing a compound of formula (I) below; and administrating to the subject the composition 

Use of a pharmaceutical composition for promoting proliferation and/or migration of skin cells, and for improving wound healing in a subject

What is disclosed in the invention is a preparation method of a supercriticalextract, which is made from the material, the dried stem of. The extract is obtained by extractingwhich is pulverized as particles with supercritical carbon dioxide fluid. Theextract or its active ingredient, subamolide A, can be used to inhibit the growth of human urothelial carcinoma cell lines. In addition, theextract (or subamolide A) is able to synergistically inhibit the growth of human urothelial carcinoma cell lines with cisplatin (CDDP) or gemcitabine (Gem). Therefore, theextract (or subamolide A) can be an anticancer drug alone, or forms a pharmaceutical composition with CDDP (or Gem) to treat with cancers in respect of urinary system.

The present invention provides aextract for inhibiting melanogenesis. The present invention also provides a composition for inhibiting melanogenesis including compounds inhibit tyrosinase activity.

Composition for inhibiting melanogenesis and use thereof

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Kaohsiung, Taiwan

Chung-Yi Chen