National Taiwan University

Other

Taipei Medical University

Chung-Ming Chen

Si-Chen Lee

Che-Wei Chang

Wan-Jou Lee

Yu-Chun Chien

Chia-Yen Lee

Jaulang Hwang

The present invention develops a vaccine composition against and treatment or prevention on inflammation and lung injury (particularly hyperoxia-induced lung injury) and progression of periodontitis. Tn immunization increases serum anti-Tn antibody titers, while it decreases lavaged protein and cytokines, and also decreases mean linear intercept and lung injury score. Furthermore, the improvement in lung injury is accompanied by a decrease in NF-&#x3ba;B activity.

Tn vaccine composition and method for alleviating inflammation

This algorithm provides a marker-free approach to establishing the pixel correspondence among the IR images taken at different times, which is the basis for quantitatively characterizing the variation of the heat energy and patterns pixel-wise on a breast surface. The idea is to use the corner points of the heat pattern and the branch points of the skeletons of the heat pattern on the body surface as the initial fiducial points for the longitudinal IR image registration. The Thin-Plate Spline technique is used to model the nonlinear deformation between two IR images taken at two different times. Mutual information between the TPS-transformed image and the target image is employed as the metric quantifying the quality of the longitudinal IR image registration. To optimize the registration, Nelder-Mead simplex method is used to locally modify the pairings of the fiducial points in the source and target IR images to maximize the mutual information.

Longitudinal image registration algorithm for infrared images for chemotherapy response monitoring and early detection of breast cancers

It is developed a Dual-Spectrum Heat Pattern Separation (DS-HPS) algorithm to quantify the energy from the area of the high temperature tissues, called qmap, and decompose the body surface into the high and normal temperature areas based on a pair of middle-wave Infra-red images and long-wave Infra-red images. Further, with longitudinal registration, we can detect the cancerous tissues and assess the chemotherapy treatment response on a pixel by pixel basis according to the change of the qmap derived by the DS-HPS algorithm. The preliminary result shows the area and the qvalues in the high temperature area are decreased as the patients receive more chemotherapy. These suggest the proposed algorithm could capture the incremental or decremental of the energies emitted by the cancerous tissues, which has the potentials for chemotherapy assessment and early detection.

Dual-spectrum heat pattern separation algorithm for assessing chemotherapy treatment response and early detection

Infra-red images of tumors carry the information of normal and cancerous tissues in every pixel. We developed a Dual-Spectrum Heat Pattern Separation (DS-HPS) algorithm to quantify the energy from the area of the high temperature tissues, called qmap, and decompose the body surface into the high and normal temperature areas based on a pair of middle-wave Infra-red images and long-wave Infra-red images. Further, with longitudinal registration, we can detect the cancerous tissues and assess the chemotherapy treatment response on a pixel by pixel basis according to the change of the qmap derived by the DS-HPS algorithm. The preliminary result shows the area and the qvalues in the high temperature area are decreased as the patients receive more chemotherapy. These suggest the proposed algorithm could capture the incremental or decremental of the energies emitted by the cancerous tissues, which has the potentials for chemotherapy assessment and early detection.

Microwavable container

A steam cleaner with multiple protections includes a machine body, in which first and second protections are provided. The first protection includes a pressure controller and a relief valve, and the second protection includes a temperature controller and a fuse unit. When a boiler provided in the machine body has an internal pressure or an internal temperature exceeded a value preset for the pressure controller or the temperature controller, respectively, a power control unit automatically power off the steam cleaner. When the boiler has an internal pressure exceeded a value preset for the relief valve, steam is immediately discharged from the boiler, and when the boiler has an internal temperature exceeded a value preset for the fuse unit, heating of the boiler is immediately stopped to avoid any danger.

Growing community of inventors

Taipei, Taiwan

Chung-Ming Chen