Dongwha Pharm. Ind. Co., Ltd.

Chung Ha Choi

Hyun S Hwang

Sung June Yoon

Dong Rack Choi

Yong Ho Chung

Hae Ran Yun

Hee Soon Lee

Jung A Lee

Sang Hun Jung

Moon Sun Lee

Eun Yi Moon

Dug Keun Lee

The present invention relates to a novel arylsulfonylimidazolone derivative represented by the following formula (I) which shows a superior antineoplastic activity in contrast to the known sulfonylurea antitumor agents as well as little side effect: ##STR1## and its pharmaceutically acceptable salt and stereoisomer, in which - -, R.sub.1, and R.sub.2 are as defined in the specification.

Arylsulfonylimidazolone derivatives as an antitumor agent

The present invention relates to a novel arylsulfonylimidazolone derivative represented by the following formula (I) which shows a superior antineoplastic activity in contrast to the known sulfonylurea antitumor agents as well as little side effect: ##STR1## and its pharmaceutically acceptable salt and stereoisomer, in which ----, R.sub.1, and R.sub.2 are as defined in the specification.

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Seoul, South Korea

Chung Ha Choi